ID:TPPC3_HUMAN DESCRIPTION: RecName: Full=Trafficking protein particle complex subunit 3; AltName: Full=BET3 homolog; FUNCTION: May play a role in vesicular transport from endoplasmic reticulum to Golgi. SUBUNIT: Homodimer. Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12. Heterodimer with TRAPPC6A. The heterodimer TRAPPC3-TRAPPC6A interacts with TRAPPC2L. SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network (By similarity). Endoplasmic reticulum (By similarity). SIMILARITY: Belongs to the TRAPP small subunits family. BET3 subfamily.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O43617
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.