Human Gene UHMK1 (ENST00000282169.8_1) from GENCODE V47lift37
  Description: U2AF homology motif kinase 1 (from HGNC UHMK1)
Gencode Transcript: ENST00000282169.8_1
Gencode Gene: ENSG00000152332.16_7
Transcript (Including UTRs)
   Position: hg19 chr1:162,467,875-162,493,844 Size: 25,970 Total Exon Count: 7 Strand: +


Page IndexSequence and LinksPrimersMalaCardsCTDRNA-Seq Expression
Other SpeciesmRNA DescriptionsPathwaysOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:162,467,875-162,493,844)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSEnsemblExonPrimerHGNCMalacardsPubMed
Wikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: UHMK1
Diseases sorted by gene-association score: median arcuate ligament syndrome (16), dracunculiasis (11), maxillary sinus cancer (11), paranasal sinus cancer (10), schizophrenia (2), kabuki syndrome 1 (1)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 22.34 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 448.87 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  KJ900116 - Synthetic construct Homo sapiens clone ccsbBroadEn_09510 UHMK1 gene, encodes complete protein.
AK058195 - Homo sapiens cDNA FLJ25466 fis, clone TST09304, highly similar to Kinase interacting with leukemia-associated gene (stathmin).
BC026046 - Homo sapiens U2AF homology motif (UHM) kinase 1, mRNA (cDNA clone MGC:39391 IMAGE:4649261), complete cds.
AJ536197 - Homo sapiens mRNA for KIS protein.
AK292369 - Homo sapiens cDNA FLJ75471 complete cds, highly similar to Homo sapiens U2AF homology motif (UHM) kinase 1 (UHMK1), mRNA.
AB384827 - Synthetic construct DNA, clone: pF1KB3640, Homo sapiens UHMK1 gene for serine/threonine-protein kinase Kist, complete cds, without stop codon, in Flexi system.
AL834136 - Homo sapiens mRNA; cDNA DKFZp667I0511 (from clone DKFZp667I0511).
BC014917 - Homo sapiens U2AF homology motif (UHM) kinase 1, mRNA (cDNA clone IMAGE:3920939), partial cds.
JD289561 - Sequence 270585 from Patent EP1572962.
JD298036 - Sequence 279060 from Patent EP1572962.
JD359206 - Sequence 340230 from Patent EP1572962.
JD501281 - Sequence 482305 from Patent EP1572962.
JD499117 - Sequence 480141 from Patent EP1572962.
JD562699 - Sequence 543723 from Patent EP1572962.
JD266708 - Sequence 247732 from Patent EP1572962.
JD495160 - Sequence 476184 from Patent EP1572962.
JD504539 - Sequence 485563 from Patent EP1572962.
JD266342 - Sequence 247366 from Patent EP1572962.
JD530645 - Sequence 511669 from Patent EP1572962.
JD226138 - Sequence 207162 from Patent EP1572962.
JD510367 - Sequence 491391 from Patent EP1572962.
JD433535 - Sequence 414559 from Patent EP1572962.
JD148560 - Sequence 129584 from Patent EP1572962.
JD145663 - Sequence 126687 from Patent EP1572962.
JD288507 - Sequence 269531 from Patent EP1572962.
JD490038 - Sequence 471062 from Patent EP1572962.

-  Biochemical and Signaling Pathways
  BioCarta from NCI Cancer Genome Anatomy Project
h_stathminPathway - Stathmin and breast cancer resistance to antimicrotubule agents

-  Other Names for This Gene
  Alternate Gene Symbols: AL834136, ENST00000282169.1, ENST00000282169.2, ENST00000282169.3, ENST00000282169.4, ENST00000282169.5, ENST00000282169.6, ENST00000282169.7, uc317jyo.1
UCSC ID: ENST00000282169.8_1
RefSeq Accession: NM_175866.5

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.