Human Gene USP28 (ENST00000696973.1_4) from GENCODE V47lift37
  Description: ubiquitin specific peptidase 28, transcript variant 25 (from RefSeq NM_001400786.1)
Gencode Transcript: ENST00000696973.1_4
Gencode Gene: ENSG00000048028.12_16
Transcript (Including UTRs)
   Position: hg19 chr11:113,668,597-113,746,294 Size: 77,698 Total Exon Count: 26 Strand: -
Coding Region
   Position: hg19 chr11:113,669,962-113,746,223 Size: 76,262 Coding Exon Count: 26 

Page IndexSequence and LinksPrimersCTDGene AllelesMicroarray Expression
RNA StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:113,668,597-113,746,294)mRNA (may differ from genome)Protein (1139 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblExonPrimerGeneCardsHGNC
MGIPubMedUniProtKB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -38.9071-0.548 Picture PostScript Text
3' UTR -350.801365-0.257 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  LF384546 - JP 2014500723-A/192049: Polycomb-Associated Non-Coding RNAs.
BC035986 - Homo sapiens ubiquitin specific peptidase 28, mRNA (cDNA clone IMAGE:4109294), with apparent retained intron.
LF376801 - JP 2014500723-A/184304: Polycomb-Associated Non-Coding RNAs.
AK027521 - Homo sapiens cDNA FLJ14615 fis, clone NT2RP1001248.
AB040948 - Homo sapiens mRNA for KIAA1515 protein, partial cds.
AK304770 - Homo sapiens cDNA FLJ58236 complete cds, highly similar to Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15).
AF266283 - Homo sapiens ubiquitin specific protease (USP28) mRNA, complete cds.
JD133479 - Sequence 114503 from Patent EP1572962.
JD240343 - Sequence 221367 from Patent EP1572962.
JD233632 - Sequence 214656 from Patent EP1572962.
JD058983 - Sequence 40007 from Patent EP1572962.
LF376799 - JP 2014500723-A/184302: Polycomb-Associated Non-Coding RNAs.
AK097623 - Homo sapiens cDNA FLJ40304 fis, clone TESTI2029227, weakly similar to UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21 (EC 3.1.2.15).
JD123012 - Sequence 104036 from Patent EP1572962.
JD427370 - Sequence 408394 from Patent EP1572962.
JD120087 - Sequence 101111 from Patent EP1572962.
LF376796 - JP 2014500723-A/184299: Polycomb-Associated Non-Coding RNAs.
LF376793 - JP 2014500723-A/184296: Polycomb-Associated Non-Coding RNAs.
LF376791 - JP 2014500723-A/184294: Polycomb-Associated Non-Coding RNAs.
LF376790 - JP 2014500723-A/184293: Polycomb-Associated Non-Coding RNAs.
LF376789 - JP 2014500723-A/184292: Polycomb-Associated Non-Coding RNAs.
LF376788 - JP 2014500723-A/184291: Polycomb-Associated Non-Coding RNAs.
BC065928 - Homo sapiens ubiquitin specific peptidase 28, mRNA (cDNA clone MGC:70638 IMAGE:6140725), complete cds.
KJ902990 - Synthetic construct Homo sapiens clone ccsbBroadEn_12384 USP28 gene, encodes complete protein.
LF376787 - JP 2014500723-A/184290: Polycomb-Associated Non-Coding RNAs.
LF376785 - JP 2014500723-A/184288: Polycomb-Associated Non-Coding RNAs.
LF376780 - JP 2014500723-A/184283: Polycomb-Associated Non-Coding RNAs.
LF376778 - JP 2014500723-A/184281: Polycomb-Associated Non-Coding RNAs.
CU688104 - Synthetic construct Homo sapiens gateway clone IMAGE:100021805 5' read USP28 mRNA.
AK304376 - Homo sapiens cDNA FLJ61554 complete cds, highly similar to Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15).
LF376773 - JP 2014500723-A/184276: Polycomb-Associated Non-Coding RNAs.
LF376772 - JP 2014500723-A/184275: Polycomb-Associated Non-Coding RNAs.
LF376771 - JP 2014500723-A/184274: Polycomb-Associated Non-Coding RNAs.
LF376769 - JP 2014500723-A/184272: Polycomb-Associated Non-Coding RNAs.
LF376768 - JP 2014500723-A/184271: Polycomb-Associated Non-Coding RNAs.
LF376767 - JP 2014500723-A/184270: Polycomb-Associated Non-Coding RNAs.
LF376758 - JP 2014500723-A/184261: Polycomb-Associated Non-Coding RNAs.
MA620123 - JP 2018138019-A/192049: Polycomb-Associated Non-Coding RNAs.
MA612378 - JP 2018138019-A/184304: Polycomb-Associated Non-Coding RNAs.
MA612376 - JP 2018138019-A/184302: Polycomb-Associated Non-Coding RNAs.
MA612373 - JP 2018138019-A/184299: Polycomb-Associated Non-Coding RNAs.
MA612370 - JP 2018138019-A/184296: Polycomb-Associated Non-Coding RNAs.
MA612368 - JP 2018138019-A/184294: Polycomb-Associated Non-Coding RNAs.
MA612367 - JP 2018138019-A/184293: Polycomb-Associated Non-Coding RNAs.
MA612366 - JP 2018138019-A/184292: Polycomb-Associated Non-Coding RNAs.
MA612365 - JP 2018138019-A/184291: Polycomb-Associated Non-Coding RNAs.
MA612364 - JP 2018138019-A/184290: Polycomb-Associated Non-Coding RNAs.
MA612362 - JP 2018138019-A/184288: Polycomb-Associated Non-Coding RNAs.
MA612357 - JP 2018138019-A/184283: Polycomb-Associated Non-Coding RNAs.
MA612355 - JP 2018138019-A/184281: Polycomb-Associated Non-Coding RNAs.
MA612350 - JP 2018138019-A/184276: Polycomb-Associated Non-Coding RNAs.
MA612349 - JP 2018138019-A/184275: Polycomb-Associated Non-Coding RNAs.
MA612348 - JP 2018138019-A/184274: Polycomb-Associated Non-Coding RNAs.
MA612346 - JP 2018138019-A/184272: Polycomb-Associated Non-Coding RNAs.
MA612345 - JP 2018138019-A/184271: Polycomb-Associated Non-Coding RNAs.
MA612344 - JP 2018138019-A/184270: Polycomb-Associated Non-Coding RNAs.
MA612335 - JP 2018138019-A/184261: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A8V8TLZ9, A0A8V8TLZ9_HUMAN, NM_001400786, uc331bro.1, uc331bro.2, USP28
UCSC ID: ENST00000696973.1_4
RefSeq Accession: NM_001346252.4

-  Gene Model Information
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-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.