ID:VOPP1_HUMAN DESCRIPTION: RecName: Full=Vesicular, overexpressed in cancer, prosurvival protein 1; AltName: Full=EGFR-coamplified and overexpressed protein; Short=ECop; AltName: Full=Glioblastoma-amplified secreted protein; AltName: Full=Putative NF-kappa-B-activating protein 055N; Flags: Precursor; FUNCTION: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=When overexpressed, localizes in the nucleus and perinuclear regions. TISSUE SPECIFICITY: Widely expressed with highest levels in thymus and ovary. SIMILARITY: Belongs to the VOPP1/ECOP family. SEQUENCE CAUTION: Sequence=AAK82888.1; Type=Erroneous translation; Note=Wrong choice of frame;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96AW1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
