ID:ZCHC8_HUMAN DESCRIPTION: RecName: Full=Zinc finger CCHC domain-containing protein 8; FUNCTION: May be involved in pre-mRNA splicing. SUBUNIT: Identified in the spliceosome C complex. INTERACTION: P38398:BRCA1; NbExp=2; IntAct=EBI-1263058, EBI-349905; PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. SIMILARITY: Belongs to the ZCCHC8 family. SIMILARITY: Contains 1 CCHC-type zinc finger.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6NZY4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
GeneReviews article(s) related to gene ZCCHC8: dkc (Dyskeratosis Congenita and Related Telomere Biology Disorders) pf (Pulmonary Fibrosis Predisposition Overview)
Gene Model Information
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for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
