Human Gene ZNF207 (ENST00000394670.9_8) from GENCODE V47lift37
  Description: zinc finger protein 207, transcript variant 3 (from RefSeq NM_001098507.2)
Gencode Transcript: ENST00000394670.9_8
Gencode Gene: ENSG00000010244.19_18
Transcript (Including UTRs)
   Position: hg19 chr17:30,677,176-30,708,904 Size: 31,729 Total Exon Count: 12 Strand: +
Coding Region
   Position: hg19 chr17:30,677,305-30,696,778 Size: 19,474 Coding Exon Count: 12 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:30,677,176-30,708,904)mRNA (may differ from genome)Protein (494 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: ZN207_HUMAN
DESCRIPTION: RecName: Full=Zinc finger protein 207;
SUBCELLULAR LOCATION: Nucleus (Probable).
TISSUE SPECIFICITY: Ubiquitous.
SIMILARITY: Contains 2 C2H2-type zinc fingers.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 23.42 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 597.90 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -32.90129-0.255 Picture PostScript Text
3' UTR -3554.6012126-0.293 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like

SCOP Domains:
48695 - Multiheme cytochromes
57667 - beta-beta-alpha zinc fingers

ModBase Predicted Comparative 3D Structure on O43670
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0008201 heparin binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding

Biological Process:
GO:0000070 mitotic sister chromatid segregation
GO:0001578 microtubule bundle formation
GO:0006355 regulation of transcription, DNA-templated
GO:0007049 cell cycle
GO:0007059 chromosome segregation
GO:0007094 mitotic spindle assembly checkpoint
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0046785 microtubule polymerization
GO:0050821 protein stabilization
GO:0051301 cell division
GO:0051983 regulation of chromosome segregation
GO:0090307 mitotic spindle assembly

Cellular Component:
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:1990047 spindle matrix


-  Descriptions from all associated GenBank mRNAs
  FV525961 - Nucleic acid controling mast cell degranulation.
HZ408710 - JP 2015528002-A/1307: CHIRAL CONTROL.
LG052044 - KR 1020150036642-A/1310: CHIRAL CONTROL.
BC002372 - Homo sapiens zinc finger protein 207, mRNA (cDNA clone MGC:8548 IMAGE:2822814), complete cds.
AK298950 - Homo sapiens cDNA FLJ58272 complete cds, highly similar to Zinc finger protein 207.
AK226172 - Homo sapiens mRNA for zinc finger protein 207 isoform a variant, clone: bm02342.
AF046001 - Homo sapiens zinc finger transcription factor (ZNF207) mRNA, complete cds.
AK309979 - Homo sapiens cDNA, FLJ17021.
AK291801 - Homo sapiens cDNA FLJ77332 complete cds, highly similar to Homo sapiens zinc finger protein 207 (ZNF207), mRNA.
BC008023 - Homo sapiens zinc finger protein 207, mRNA (cDNA clone MGC:15953 IMAGE:3538197), complete cds.
AB209215 - Homo sapiens mRNA for zinc finger protein 207 variant protein.
BC000962 - Homo sapiens cDNA clone IMAGE:3446353, containing frame-shift errors.
JD255376 - Sequence 236400 from Patent EP1572962.
JD025779 - Sequence 6803 from Patent EP1572962.
JD557042 - Sequence 538066 from Patent EP1572962.
JD032887 - Sequence 13911 from Patent EP1572962.
KJ905956 - Synthetic construct Homo sapiens clone ccsbBroadEn_15626 ZNF207 gene, encodes complete protein.
CU675901 - Synthetic construct Homo sapiens gateway clone IMAGE:100019221 5' read ZNF207 mRNA.
AB385067 - Synthetic construct DNA, clone: pF1KB5227, Homo sapiens ZNF207 gene for zinc finger protein 207, complete cds, without stop codon, in Flexi system.
BT007365 - Homo sapiens zinc finger protein 207 mRNA, complete cds.
JF432111 - Synthetic construct Homo sapiens clone IMAGE:100073250 zinc finger protein 207 (ZNF207) gene, encodes complete protein.
AL834501 - Homo sapiens mRNA; cDNA DKFZp761N202 (from clone DKFZp761N202).
JD211043 - Sequence 192067 from Patent EP1572962.
JD074435 - Sequence 55459 from Patent EP1572962.
JD562990 - Sequence 544014 from Patent EP1572962.
JD333149 - Sequence 314173 from Patent EP1572962.
JD548743 - Sequence 529767 from Patent EP1572962.
JD529410 - Sequence 510434 from Patent EP1572962.
JD169672 - Sequence 150696 from Patent EP1572962.
JD169673 - Sequence 150697 from Patent EP1572962.
JD125631 - Sequence 106655 from Patent EP1572962.
JD395431 - Sequence 376455 from Patent EP1572962.
JD491985 - Sequence 473009 from Patent EP1572962.
JD388525 - Sequence 369549 from Patent EP1572962.
JD457244 - Sequence 438268 from Patent EP1572962.
JD522971 - Sequence 503995 from Patent EP1572962.
JD118599 - Sequence 99623 from Patent EP1572962.
JD533872 - Sequence 514896 from Patent EP1572962.
DQ584967 - Homo sapiens piRNA piR-52079, complete sequence.
AK026215 - Homo sapiens cDNA: FLJ22562 fis, clone HSI01814.

-  Other Names for This Gene
  Alternate Gene Symbols: A8K6Y6, BUGZ , E1P660, E1P661, E1P662, ENST00000394670.1, ENST00000394670.2, ENST00000394670.3, ENST00000394670.4, ENST00000394670.5, ENST00000394670.6, ENST00000394670.7, ENST00000394670.8, NM_001098507, O43670, Q53XS9, Q96HW5, Q9BUQ7, uc318wux.1, uc318wux.2, ZN207_HUMAN, ZNF207
UCSC ID: ENST00000394670.9_8
RefSeq Accession: NM_001098507.2
Protein: O43670 (aka ZN207_HUMAN or Z207_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.