Human Gene ZNF585B (ENST00000392156.7_4) from GENCODE V47lift37

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Description: zinc finger protein 585B (from HGNC ZNF585B)
Gencode Transcript: ENST00000392156.7_4
Gencode Gene: ENSG00000245680.11_13
Transcript (Including UTRs)
Position: hg19 chr19:37,680,605-37,701,451 Size: 20,847 Total Exon Count: 5 Strand: -
Coding Region
Position: hg19 chr19:37,689,858-37,698,013 Size: 8,156 Coding Exon Count: 2

Page Index	Sequence and Links	UniProtKB Comments	Primers	CTD	Gene Alleles
RNA-Seq Expression	Microarray Expression	RNA Structure	Protein Structure	Other Species	mRNA Descriptions
Other Names	Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr19:37,680,605-37,701,451)			mRNA (may differ from genome)		Protein (56 aa)
Gene Sorter	Genome Browser	Other Species FASTA	Gene interactions	Table Schema	AlphaFold
BioGPS	Ensembl	ExonPrimer	GeneCards	HGNC	MGI
PubMed	UniProtKB	Wikipedia

Comments and Description Text from UniProtKB


	ID: E9PNT4_HUMAN DESCRIPTION: SubName: Full=Zinc finger protein 585B; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D004397 Fonofos D010278 Parathion C012568 terbufos C024746 tobacco tar

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 5.89 RPKM in Pituitary Total median expression: 149.10 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-78.70	234	-0.336	Picture	PostScript	Text
3' UTR	-54.30	195	-0.278	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Protein Domain and Structure Information

ModBase Predicted Comparative 3D Structure on E9PNT4


Front	Top	Side

The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog

Descriptions from all associated GenBank mRNAs


	AK098695 - Homo sapiens cDNA FLJ25829 fis, clone TST08126. AK094989 - Homo sapiens cDNA FLJ37670 fis, clone BRHIP2011933, highly similar to Zinc finger protein 585B. AY147015 - Homo sapiens zinc finger protein 41-like protein mRNA, complete cds. BC093625 - Homo sapiens zinc finger protein 585B, mRNA (cDNA clone MGC:120660 IMAGE:7939470), complete cds. EU446556 - Synthetic construct Homo sapiens clone IMAGE:100069942; IMAGE:100011765; FLH257105.01L zinc finger protein 585B (ZNF585B) gene, encodes complete protein. BC051277 - Homo sapiens zinc finger protein 585B, mRNA (cDNA clone IMAGE:6250801), containing frame-shift errors. BC067088 - Homo sapiens zinc finger protein 585B, mRNA (cDNA clone IMAGE:6208925), partial cds. BC080550 - Homo sapiens zinc finger protein 585B, mRNA (cDNA clone IMAGE:6249350). JD109341 - Sequence 90365 from Patent EP1572962. JD489776 - Sequence 470800 from Patent EP1572962. JD216322 - Sequence 197346 from Patent EP1572962. JD170893 - Sequence 151917 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: AY147015, E9PNT4, E9PNT4_HUMAN, ENST00000392156.1, ENST00000392156.2, ENST00000392156.3, ENST00000392156.4, ENST00000392156.5, ENST00000392156.6, uc318uwn.1, ZNF585B UCSC ID: ENST00000392156.7_4 RefSeq Accession: NM_152279.4 Protein: E9PNT4

Gene Model Information


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Methods, Credits, and Use Restrictions


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