Human Gene ZNF609 (ENST00000326648.5_4) from GENCODE V47lift37
  Description: zinc finger protein 609 (from RefSeq NM_015042.2)
Gencode Transcript: ENST00000326648.5_4
Gencode Gene: ENSG00000180357.10_8
Transcript (Including UTRs)
   Position: hg19 chr15:64,752,777-64,978,267 Size: 225,491 Total Exon Count: 10 Strand: +
Coding Region
   Position: hg19 chr15:64,791,619-64,973,581 Size: 181,963 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr15:64,752,777-64,978,267)mRNA (may differ from genome)Protein (1411 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: ZN609_HUMAN
DESCRIPTION: RecName: Full=Zinc finger protein 609;
SUBCELLULAR LOCATION: Nucleus (Probable).
SIMILARITY: Contains 1 C2H2-type zinc finger.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 13.20 RPKM in Testis
Total median expression: 279.16 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -180.60388-0.465 Picture PostScript Text
3' UTR -1456.404382-0.332 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like

SCOP Domains:
57667 - beta-beta-alpha zinc fingers

ModBase Predicted Comparative 3D Structure on O15014
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details Gene Details  
Gene SorterGene Sorter Gene Sorter  
 RGDEnsembl   
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

Biological Process:
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0007275 multicellular organism development
GO:0007517 muscle organ development
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:2000291 regulation of myoblast proliferation
GO:2001224 positive regulation of neuron migration

Cellular Component:
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0032039 integrator complex


-  Descriptions from all associated GenBank mRNAs
  BC000648 - Homo sapiens zinc finger protein 609, mRNA (cDNA clone IMAGE:3344699), partial cds.
BC014251 - Homo sapiens zinc finger protein 609, mRNA (cDNA clone IMAGE:4635290), partial cds.
BC084543 - Homo sapiens zinc finger protein 609, mRNA (cDNA clone IMAGE:4646886).
BC009226 - Homo sapiens zinc finger protein 609, mRNA (cDNA clone IMAGE:3947458), partial cds.
BC142647 - Homo sapiens zinc finger protein 609, mRNA (cDNA clone IMAGE:40147971), complete cds.
DQ596326 - Homo sapiens piRNA piR-34392, complete sequence.
JD194586 - Sequence 175610 from Patent EP1572962.
JD135594 - Sequence 116618 from Patent EP1572962.
JD423458 - Sequence 404482 from Patent EP1572962.
JD185283 - Sequence 166307 from Patent EP1572962.
JD095941 - Sequence 76965 from Patent EP1572962.
JD323544 - Sequence 304568 from Patent EP1572962.
BC029441 - Homo sapiens zinc finger protein 609, mRNA (cDNA clone IMAGE:4614377), partial cds.
AB002293 - Homo sapiens mRNA for KIAA0295 gene, partial cds.
DQ581678 - Homo sapiens piRNA piR-49790, complete sequence.
JD287751 - Sequence 268775 from Patent EP1572962.
JD280054 - Sequence 261078 from Patent EP1572962.
BC110401 - Homo sapiens zinc finger protein 609, mRNA (cDNA clone IMAGE:5557526), partial cds.
JD087804 - Sequence 68828 from Patent EP1572962.
JD351308 - Sequence 332332 from Patent EP1572962.
BC050315 - Homo sapiens zinc finger protein 609, mRNA (cDNA clone IMAGE:4822457).
JD352382 - Sequence 333406 from Patent EP1572962.
JD163932 - Sequence 144956 from Patent EP1572962.
JD540362 - Sequence 521386 from Patent EP1572962.
JD497409 - Sequence 478433 from Patent EP1572962.
JD384083 - Sequence 365107 from Patent EP1572962.
JD530110 - Sequence 511134 from Patent EP1572962.
JD187071 - Sequence 168095 from Patent EP1572962.
JD110227 - Sequence 91251 from Patent EP1572962.
JD366072 - Sequence 347096 from Patent EP1572962.
JD294661 - Sequence 275685 from Patent EP1572962.
JD438931 - Sequence 419955 from Patent EP1572962.
JD475242 - Sequence 456266 from Patent EP1572962.
JD521713 - Sequence 502737 from Patent EP1572962.
JD230742 - Sequence 211766 from Patent EP1572962.
JD293810 - Sequence 274834 from Patent EP1572962.
JD432175 - Sequence 413199 from Patent EP1572962.
JD547494 - Sequence 528518 from Patent EP1572962.
JD249229 - Sequence 230253 from Patent EP1572962.
JD545375 - Sequence 526399 from Patent EP1572962.
JD446890 - Sequence 427914 from Patent EP1572962.
JD186977 - Sequence 168001 from Patent EP1572962.
JD486057 - Sequence 467081 from Patent EP1572962.
JD086128 - Sequence 67152 from Patent EP1572962.
JD392311 - Sequence 373335 from Patent EP1572962.
JD153558 - Sequence 134582 from Patent EP1572962.
JD355801 - Sequence 336825 from Patent EP1572962.
JD353568 - Sequence 334592 from Patent EP1572962.
JD477812 - Sequence 458836 from Patent EP1572962.
JD126551 - Sequence 107575 from Patent EP1572962.
JD146397 - Sequence 127421 from Patent EP1572962.
JD453299 - Sequence 434323 from Patent EP1572962.
JD271932 - Sequence 252956 from Patent EP1572962.
JD170810 - Sequence 151834 from Patent EP1572962.
JD081149 - Sequence 62173 from Patent EP1572962.
JD287837 - Sequence 268861 from Patent EP1572962.
JD183424 - Sequence 164448 from Patent EP1572962.
JD391894 - Sequence 372918 from Patent EP1572962.
JD326762 - Sequence 307786 from Patent EP1572962.
JD068811 - Sequence 49835 from Patent EP1572962.
JD154722 - Sequence 135746 from Patent EP1572962.
JD207074 - Sequence 188098 from Patent EP1572962.
JD137134 - Sequence 118158 from Patent EP1572962.
JD334393 - Sequence 315417 from Patent EP1572962.
JD334394 - Sequence 315418 from Patent EP1572962.
JD385613 - Sequence 366637 from Patent EP1572962.
JD387121 - Sequence 368145 from Patent EP1572962.
JD450319 - Sequence 431343 from Patent EP1572962.
JD456152 - Sequence 437176 from Patent EP1572962.
JD330220 - Sequence 311244 from Patent EP1572962.
JD174491 - Sequence 155515 from Patent EP1572962.
JD396425 - Sequence 377449 from Patent EP1572962.
JD239862 - Sequence 220886 from Patent EP1572962.
JD299043 - Sequence 280067 from Patent EP1572962.
JD285076 - Sequence 266100 from Patent EP1572962.
JD387942 - Sequence 368966 from Patent EP1572962.
JD387477 - Sequence 368501 from Patent EP1572962.
JD104577 - Sequence 85601 from Patent EP1572962.
JD071754 - Sequence 52778 from Patent EP1572962.
JD465901 - Sequence 446925 from Patent EP1572962.
JD540865 - Sequence 521889 from Patent EP1572962.
JD075759 - Sequence 56783 from Patent EP1572962.
JD218391 - Sequence 199415 from Patent EP1572962.
JD454230 - Sequence 435254 from Patent EP1572962.
JD164121 - Sequence 145145 from Patent EP1572962.
JD437477 - Sequence 418501 from Patent EP1572962.
JD134455 - Sequence 115479 from Patent EP1572962.
JD267730 - Sequence 248754 from Patent EP1572962.
JD058899 - Sequence 39923 from Patent EP1572962.
JD403474 - Sequence 384498 from Patent EP1572962.
JD393212 - Sequence 374236 from Patent EP1572962.
JD486383 - Sequence 467407 from Patent EP1572962.
JD072554 - Sequence 53578 from Patent EP1572962.
JD385787 - Sequence 366811 from Patent EP1572962.
JD225967 - Sequence 206991 from Patent EP1572962.
JD141152 - Sequence 122176 from Patent EP1572962.
JD202143 - Sequence 183167 from Patent EP1572962.
JD520141 - Sequence 501165 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000326648.1, ENST00000326648.2, ENST00000326648.3, ENST00000326648.4, KIAA0295 , NM_015042, O15014, Q0D2I2, uc317scj.1, uc317scj.2, ZN609_HUMAN, ZNF609
UCSC ID: ENST00000326648.5_4
RefSeq Accession: NM_015042.2
Protein: O15014 (aka ZN609_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.