Gene interactions and pathways from curated databases and text-mining
Nature structural & molecular biology 2007, PMID: 17721549

YY1 functions with INO80 to activate transcription.

Cai, Yong; Jin, Jingji; Yao, Tingting; Gottschalk, Aaron J; Swanson, Selene K; Wu, Su; Shi, Yang; Washburn, Michael P; Florens, Laurence; Conaway, Ronald C; Conaway, Joan W

Ubiquitously expressed transcription factor Yin-Yang-1 (YY1) controls expression of many genes. YY1 is tightly associated with the human ATP-dependent INO80-like chromatin-remodeling complex (INO80). INO80 is recruited by YY1 to YY1-activated genes, where it functions as an essential coactivator. Binding of YY1 to its DNA sites in target genes requires INO80, suggesting that YY1 uses the INO80 complex not only to activate transcription but also to gain access to target promoters.

Document information provided by NCBI PubMed

Text Mining Data

YY1 → INO80: " Binding of YY1 to its DNA sites in target genes requires INO80 , suggesting that YY1 uses the INO80 complex not only to activate transcription but also to gain access to target promoters "

Manually curated Databases

  • IRef Biogrid Interaction: TFPT — UCHL5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — INO80 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — ACTL6A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NFRKB — UCHL5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — INO80E (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — ACTL6A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR8 — INO80 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80 — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80 — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80 — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80 — INO80D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: H2AFZ — RUVBL2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TFPT — TFPT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR8 — INO80E (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80E — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — INO80D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — TFPT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: H2AFZ — ACTL6A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80E — TFPT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TFPT — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80E — INO80D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR5 — INO80D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTL6A — INO80D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR5 — ACTL6A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NFRKB — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — ACTR5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTL6A — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTL6A — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80D — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80E — ACTL6A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR5 — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR5 — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — INO80E (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — YY1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — YY1 (colocalization, imaging technique)
  • IRef Biogrid Interaction: INO80D — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — INO80E (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — ACTR8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80E — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR5 — INO80E (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTL6A — TFPT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — ACTR8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — INO80D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — TFPT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — H2AFZ (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR5 — TFPT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR8 — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR8 — INO80D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR8 — ACTL6A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HSPA5 — YY1 (colocalization, imaging technique)
  • IRef Biogrid Interaction: ACTR8 — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — INO80B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — RUVBL2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TFPT — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — ACTR5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TFPT — INO80D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — INO80E (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR8 — TFPT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — INO80B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — INO80D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — TFPT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — INO80C (colocalization, imaging technique)
  • IRef Biogrid Interaction: NFRKB — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — UCHL5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR5 — UCHL5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTL6A — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR8 — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80E — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR5 — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — TCF3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80D — UCHL5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: H2AFZ — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80E — TCF3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80D — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80C — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — UCHL5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80C — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — NFRKB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TFPT — INO80C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — ACTL6A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80B — INO80D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: UCHL5 — MCRS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — INO80 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80 — TFPT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80 — YY1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80 — YY1 (colocalization, imaging technique)
  • IRef Biogrid Interaction: ACTR8 — YY1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR8 — RUVBL2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — YY1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — INO80 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80E — UCHL5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL1 — RUVBL2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR8 — UCHL5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — YY1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — YY1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — UCHL5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — ACTL6A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ACTR8 — ACTR5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YY1 — ACTR5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80 — INO80E (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INO80 — ACTR5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — ACTR5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RUVBL2 — TFPT (physical association, affinity chromatography technology)
In total, 111 gene pairs are associated to this article in curated databases