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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining
Science 2010, PMID: 20360068

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

Hutchins, James R A; Toyoda, Yusuke; Hegemann, Björn; Poser, Ina; Hériché, Jean-Karim; Sykora, Martina M; Augsburg, Martina; Hudecz, Otto; Buschhorn, Bettina A; Bulkescher, Jutta; Conrad, Christian; Comartin, David; Schleiffer, Alexander; Sarov, Mihail; Pozniakovsky, Andrei; Slabicki, Mikolaj Michal; Schloissnig, Siegfried; Steinmacher, Ines; Leuschner, Marit; Ssykor, Andrea; Lawo, Steffen; Pelletier, Laurence; Stark, Holger; Nasmyth, Kim; Ellenberg, Jan; Durbin, Richard; Buchholz, Frank; Mechtler, Karl; Hyman, Anthony A; Peters, Jan-Michael

Chromosome segregation and cell division are essential, highly ordered processes that depend on numerous protein complexes. Results from recent RNA interference screens indicate that the identity and composition of these protein complexes is incompletely understood. Using gene tagging on bacterial artificial chromosomes, protein localization, and tandem-affinity purification-mass spectrometry, the MitoCheck consortium has analyzed about 100 human protein complexes, many of which had not or had only incompletely been characterized. This work has led to the discovery of previously unknown, evolutionarily conserved subunits of the anaphase-promoting complex and the gamma-tubulin ring complex--large complexes that are essential for spindle assembly and chromosome segregation. The approaches we describe here are generally applicable to high-throughput follow-up analyses of phenotypic screens in mammalian cells.

Document information provided by NCBI PubMed

Text Mining Data

Dashed line = No text mining data

Manually curated Databases

  • IRef Biogrid Interaction: MIS12 — NDC80 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: AURKA — AURKA (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1 — CASC5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CDC20 — CDC16 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CHORDC1 — CHORDC1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1B — ANAPC7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — TF (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PACS1 — FGFR1OP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WAPAL — SMC3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DDX5 — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PTTG1 — PTTG1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TTBK2 — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SLAIN2 — CKAP5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBA3E — AIFM1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WAPAL — STAG1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: LLGL2 — PRKCI (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — LMNB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1B — BUB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — CYR61 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1B — BUB1B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBA3E — PFDN2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBA3E — PFDN5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NDC80 — NDC80 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: LLGL2 — LLGL2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — PIGR (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SNAP29 — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PTTG1 — DECR1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PARD6B — LLGL2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CEP350 — FGFR1OP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1 — SPC25 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SMC1A — WAPAL (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1B — MIS12 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1 — NUF2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1 — NSL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — NSL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TACC3 — CKAP5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — CNBP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — HNRNPF (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — RCN1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — CENPC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1 — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOGA2 — MARK2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1B — ANAPC4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — FGA (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1 — BUB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: UBR5 — BUB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: FGFR1OP — FGFR1OP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBA3E — PFDN6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — APOA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — SERPINA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: HNRNPH1 — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — CENPC (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — FGB (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — BUB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WAPAL — WAPAL (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — CASC5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — HP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CKAP5 — TACC2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NDC80 — BUB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — NUF2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TRIM28 — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — SPC25 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WAPAL — PDS5A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MARK2 — MARK2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — SMTN (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NDC80 — SPC24 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — SPC24 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WAPAL — STAG2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — DDX17 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1 — SPC24 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — SPC24 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: AURKA — CALU (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DSN1 — BUB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBA3E — VBP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZWINT — TRIM5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RRBP1 — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBA3E — PFDN4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SNW1 — CKAP5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBA3E — TIMM50 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CEP192 — AURKA (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — SPC25 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CKAP5 — CKAP5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ATM — ATM (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NDC80 — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WAPAL — PDS5B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PARD6A — LLGL2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CDC16 — ANAPC1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WAPAL — RAD21 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DSN1 — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — CASC5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — NUF2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NDC80 — SPC25 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: AURKA — TPX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1B — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — DSN1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PTTG1 — ESPL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CDCA5 — CDCA5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TTK — TTK (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CDC16 — ANAPC7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — NSL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1B — CDC20 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — ZWINT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BUB1B — CDC27 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MIS12 — MIS12 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NDC80 — NUF2 (physical association, affinity chromatography technology)
  • Gene Ontology Complexes gamma-tubulin ring complex: gamma-tubulin ring complex complex (MZT1-MZT2A-TUBGCP5)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CENPE-CLASP1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 17 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of FBXL3-CRY1-PER1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ACAD8-NEK2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of NAA50-NAA15-HYPK-NAA10 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of KPNB1-RPA2-SSBP1-RMI2-BLM (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of DDX6-LSM14A-C1QBP-PRMT1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 15 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of KPNA6-KPNA1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 19 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of AHSG-SMAD3-LEMD3 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of KPNA6-DDX21-KPNA1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 36 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of C21orf91-SSBP1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of HAUS2-HAUS1-HAUS6-HAUS8-HAUS3-HAUS7-HAUS5 (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 15 proteins (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TUBGCP2-CEP170-KIF4A (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of SPRR2E-SPRR2A-SPRR2B-THEM6 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of STK38-MOB1A-MOB1B-MOB2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of KIFC1-KPNB1-RANGAP1-RANBP2-NUP153-NUP50-KPNA2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of DNAJB1-DNAJB4-TTLL12 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 12 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PRMT1-CNBP (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CETN2-POC5-RAD23B-CETN3-XPC (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of KIF23-MICAL3-CD2AP-MICAL3-PRC1-SH3KBP1-CAPZA2-RACGAP1-SHCBP1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 14 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CUL4B-COPS2-DTL-COPS4-DDB1-CUL4A-COPS6 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 32 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of RAD21-SMC3-WAPAL-PDS5A-SMC1A-STAG1-PDS5B-STAG2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of DDX41-NKAP (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CDC6-BCLAF1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 18 proteins (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of HAUS6-HAUS8-HAUS5-HAUS3-HAUS7 (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of BAP1-ASXL2-HCFC1-ASXL1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of BLM-RMI1-SSBP1-PLK1-RMI2-ERCC6L (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of RAI14-MPRIP-CDK1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 12 proteins (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of LCN1P1-SMC3-RAD21-SMC1A-AURKB-PDS5B-STAG2-LCN1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 16 proteins (association, tandem affinity purification)
  • IRef Intact Interaction: CHORDC1 — CHORDC1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TGM1-TTK (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TUBGCP2-TUBG1-TUBGCP3-TUBGCP5-TUBGCP2-TUBGCP5-TUBG1-TUBGCP3 (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of NME1-CDKN2A-DNAJA4-THBS1-TCP11L1-ARL2-DNAJA1-DNAJA2-TBCD (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PPP2R3C-PPP2CB-SHCBP1-FGFR1OP-PPP2CA (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 13 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of MISP-AURKA-CEP192-FOLR1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 25 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PACS1-FGFR1OP-FGFR1OP (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 22 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 17 proteins (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ESCO1-TTBK2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 23 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 39 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 15 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 30 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 29 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 13 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of RPA2-PAFAH1B1-NDEL1-NDE1-SYNE1-CCSER2-DIXDC1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of NUP88-TEN1-CTC1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 15 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 22 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 15 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 22 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 15 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of SPC25-NDC80-NUF2-SPC24-NDC80 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 31 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 19 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CDCA8-PTRF-INCENP-RPL17-BIRC5-AURKA-AURKB (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CANX-TOR1AIP1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CEP170P1-SERPINB6-CEP170-CEP170P1-BEGAIN-CCAR2-KIFC3-SNAPIN (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CEP135-TTN-WRAP73 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of NSL1-SPC24-MIS12-CASC5-ZWINT-NUF2-DSN1-NDC80-PMF1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TUBG1-TUBGCP3-TUBGCP2-MZT2B (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of MARK2-MTCL1-MARK2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 13 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 27 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of L3MBTL2-LIN37-LIN52-LIN9-RBBP4-MYBL1-LIN54-MYBL2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TMED7-GORASP1-TMED4-LRRFIP2-LGALS3BP-TMED2-KIF14 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of DYNLL1-SERBP1-HNRNPD-KNSTRN-CEP152-CENPF-CEP63-DYNLL2-SPAG5 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 17 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 30 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 18 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TOP2A-ITPR1-TOP2B-ZNF451 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TPX2-AURKA-CEP192-AURKA-CALU (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 52 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 38 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 21 proteins (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of OGG1-LAMB1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 19 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 23 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of DDX49-SHCBP1-KIF23-RACGAP1-ALDH3B1-PDIA4-GPC5 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 19 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: ATM — ATM (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of XPO1-FABP3-XDH (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of EDC3-AP2A1-HADHA-HADHB-AP2M1-DCP2-EDC4-CCDC101-PATL1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of HNRNPH1-PLOD1-PRMT5-HNRNPA1-WDR77 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CEP120-SPICE1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 12 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of SPAG5-KNSTRN-MYCBP (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ARF3-ARF1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ANAPC7-CDC16-ANAPC1-CDC20 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of RAB8A-SYTL4-MICALL2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PPIA-MAD1L1-MAD2L1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TIMM50-VBP1-PFDN6-PFDN4-PFDN2-PFDN5-TUBA3E-TUBA3E (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of BUB1B-BUB1B-ANAPC7-ANAPC4-CDC27-CDC20 (physical association, tandem affinity purification)
  • IRef Intact Interaction: TUBG1 — MZT2B (physical association, cosedimentation through density gradient)
  • IRef Intact Interaction: Complex of RMI1-RPA3-BLM-RPA2-PGAM5-SSBP1-NDUFAF7-RMI2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 11 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PTTG1-DECR1-PTTG1-ESPL1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TIPIN-TIMELESS-CRY1-RPA2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PDCL3-PDCD5-CCT7 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ITPRIP-RASSF1-MAP1S-TMEM109-STK4-VAPB-STK3-VAPA (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PRMT1-TAF15 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of NUP88-NUP93-OGT-NUP98-NUP188-NUP214-RAE1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CDC16-ANAPC16-ANAPC10 (physical association, cosedimentation through density gradient)
  • IRef Intact Interaction: Complex of 16 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: CDCA5 — CDCA5 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of RPL17-INCENP-CDCA8-RCN1-EMD-AURKB-AKAP8 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of DYNC1I2-DYNC1LI2-DYNC1H1-DYNLL1-DYNC1LI1-DYNLRB1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of VAPB-RMDN3 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of UBR5-CEP78-VPRBP-SQSTM1-NSUN2-NAP1L4 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ACTR1A-DCTN6-ACTR1B-ACTR10-DCTN1-CAPZA2-DCTN4-DCTN5-DCTN3 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of GOLGA3-RAB14-CNTRL-SNAP29 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PARD6B-LLGL2-LLGL2-PARD6A-PRKCI (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of MAFG-ARF3-ARF1-FAM83D-BACH1-MAFF-DYNLL1-MAFK-HMMR (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 18 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 14 proteins (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of KLHL42-LGALS3BP-CUL3 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of HAUS5-HAUS6-HAUS3-HAUS7-HAUS8-HAUS1 (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TPM1-RAI14-TPM2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of AZGP1-WFDC2-BPIFB1-IKBIP-TCN1-BPIFA1-LTF (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ARRB1-NAA50-HYPK-NAA16-NAA10-NAA15 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of WDR82-PPP1CA-PPP1R10-PPP1CB-PPP1R2-TERF2-ZC3H4-TOX4 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ZWILCH-KNTC1-RINT1-ZW10-NBAS-CKAP5-C19orf25-SCFD2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of SYCP1-PIP-UBA1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CCT2-PDCL3 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 15 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PLOD1-RPA2-FAM107B-PLOD2-DYNLL1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TOP3A-BLM-PLK1 (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of BLM-RMI1-TOP3A (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PCF11-CLP1-TSEN54-TSEN2-CDKN2AIP-POLR2A-TSEN15-SSB (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PTMS-NACAP1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 17 proteins (association, anti bait coimmunoprecipitation)
  • IRef Intact Interaction: Complex of ATM-CUL4A-LMNB1-DCAF6-DDB1-DCAF8 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ALDH18A1-MICAL3-SSB-GNAI3 (physical association, tandem affinity purification)
  • IRef Intact Interaction: TTK — TTK (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of WAPAL-SMC3-STAG2-WAPAL-STAG1-PDS5B-RAD21-SMC1A-PDS5A (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of C1QBP-CCNB1-ESPL1-CDK1-PTTG1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of NUP88-XPO1-RAN (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of MISP-CHCHD3-SPECC1-GNAI3-RPA2-GNG12-GNB1-GNB2-GNB4 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ORC2-ORC3-ORC5-LRWD1-ORC1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of HDAC6-PLAA (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of MKI67-POP1-WDR18-HJURP-HAUS6 (physical association, tandem affinity purification)
  • IRef Intact Interaction: TUBG1 — MZT1 (physical association, cosedimentation through density gradient)
  • IRef Intact Interaction: Complex of TUBGCP2-TUBGCP5-MZT2B-TUBG1-TUBGCP3 (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 12 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of KCTD5-CKAP5-KCTD2 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PAPSS1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 26 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TACC3-CKAP5 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CEP131-MIB1-IPO5-PCM1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PCMTD1-TIMELESS-RPA2-RPA3-TIPIN-BCLAF1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TUBG1-TUBGCP2-TUBGCP3-TUBGCP5-MZT1 (association, tandem affinity purification)
  • IRef Intact Interaction: ERCC6L — PLK1 (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of TUBG1-TUBGCP2-TUBGCP3-TUBGCP5 (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 19 proteins (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 13 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 18 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PIP-SPRR1B-GDI2-RAB5C (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CDC27-ANAPC16-ANAPC2-CDC27-ANAPC2-ANAPC16 (association, anti bait coimmunoprecipitation)
  • IRef Intact Interaction: Complex of CHMP3-CHMP4B (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of STK38-CHEK2-JPH1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of UBR5-XPNPEP3 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of ANAPC16-BUB1B-CDC20-ANAPC5-CDC27-ANAPC7-ANAPC1-CDC23 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of BUB1B-CDC27-CDC20-CDC16-ANAPC5-ANAPC7-ANAPC1-ANAPC16 (association, tandem affinity purification)
  • IRef Intact Interaction: Complex of RAE1-NUP98-OGT-NUP188-RAN-NUP88-XPO1-PKM-NUP93 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CEP290-TPM1-PIP (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of 19 proteins (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of C17orf70-FANCB-FANCE-LASP1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of NAA10-NAA50 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of HAUS7-HAUS8-HAUS4-HAUS6-HAUS3-HAUS1-HAUS5 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of NEDD1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of NDNL2-RAD18-NSMCE1-NSMCE4A-SMC5-SMC6-NSMCE2-TUFT1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of CCT3-WDR77-PDCD5-PDCL3-IGBP1 (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of PPP2R1A-PPP2R5A-SGOL1-PPP2R5D (physical association, tandem affinity purification)
  • IRef Intact Interaction: Complex of RMI1-BLM-TOP3A-PLK1-ERCC6L (association, tandem affinity purification)
In total, 9409 gene pairs are associated to this article in curated databases