Gene interactions and pathways from curated databases and text-mining
PloS one 2013, PMID: 23667531

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

Cox, Jesse L; Wilder, Phillip J; Gilmore, Joshua M; Wuebben, Erin L; Washburn, Michael P; Rizzino, Angie

Medulloblastomas and glioblastomas, the most common primary brain tumors in children and adults, respectively, are extremely difficult to treat. Efforts to identify novel proteins essential for the growth of these tumors may help to further our understanding of the biology of these tumors, as well as, identify targets for future therapies. The recent identification of multiple transcription factor-centric protein interaction landscapes in embryonic stem cells has identified numerous understudied proteins that are essential for the self-renewal of these stem cells. To identify novel proteins essential for the fate of brain tumor cells, we examined the protein interaction network of the transcription factor, SOX2, in medulloblastoma cells. For this purpose, Multidimensional Protein Identification Technology (MudPIT) identified >280 SOX2-associated proteins in the medulloblastoma cell line DAOY. To begin to understand the roles of SOX2-associated proteins in brain cancer, we focused on two SOX2-associated proteins, Musashi 2 (MSI2) and Ubiquitin Specific Protease 9x (USP9X). Recent studies have implicated MSI2, a putative RNA binding protein, and USP9X, a deubiquitinating enzyme, in several cancers, but not brain tumors. We demonstrate that knockdown of MSI2 significantly reduces the growth of DAOY cells as well as U87 and U118 glioblastoma cells. We also demonstrate that the knockdown of USP9X in DAOY, U87 and U118 brain tumor cells strongly reduces their growth. Together, our studies identify a large set of SOX2-associated proteins in DAOY medulloblastoma cells and identify two proteins, MSI2 and USP9X, that warrant further investigation to determine whether they are potential therapeutic targets for brain cancer.

Diseases/Pathways annotated by Medline MESH: Brain Neoplasms
Document information provided by NCBI PubMed

Text Mining Data

Dashed line = No text mining data

Manually curated Databases

  • IRef Biogrid Interaction: HDAC3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MTA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CHD7 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — GATAD2A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — RBBP4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MYEF2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — NCOR1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ARID1A — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CUX1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DNAJA2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SMARCB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — DAP3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — DNAJB6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — PHC3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ARMC8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — DNM1L (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MSL1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IRF2BP1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — FAM21B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — USP9X (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CDC26 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — PPP2R5C (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TCF12 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PAPD4 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: FOXC1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TRIM26 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — WDR26 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CHD8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MAGEC1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RAE1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — INTS2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TP73 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — OLA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SKIV2L2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ANAPC1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MRPL1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — BAG2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — USP34 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CHD9 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: WDR3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — NAP1L4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TNRC18 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MRPS26 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PPIH — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SPEN (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MEPCE — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — RUNX1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — BMI1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SSB — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SCFD1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: AKAP11 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ZNF644 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — HSD17B10 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SGOL2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ZEB2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ZNF462 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — RANGAP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SART3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RANBP10 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GPN1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MRPL15 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SUPT5H (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — EPS8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BOD1L1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PPP6R1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ZNF609 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IPO7 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — LAS1L (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: LARP1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RALY — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SLFN11 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CNOT3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TUBB3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TAF6L — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ANAPC2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PELP1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — RFX1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MBD2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — PHC2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IPO5 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CTR9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CASC5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SETD2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — NIP7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: POLR2C — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SIN3B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SHCBP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RMND5B — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TNPO3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CYR61 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RMND5A — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GPC4 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ARID3B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: POP1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — RPP30 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CPSF3L (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — UTP14A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GID8 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — NUP93 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBG1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TSHZ3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CSNK2A2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ARHGAP1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SP2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — PRPF4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZNF787 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — INTS3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CHD6 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — PATZ1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CUL9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — NCAPD2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: OSBPL11 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MRPL12 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ZNF536 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MAGEC2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — IQGAP3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: C1QBP — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MAGED2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SAP130 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZFHX4 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZDBF2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TRERF1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ANP32E (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — USP15 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ETV6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PWP1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: LOX — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CLOCK — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MECOM (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SRP68 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TRIM33 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SAMD4B (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ZMYND8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MACF1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — RBM15 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: LGALS3BP — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — LSM2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RNH1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TSPYL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SENP3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CBX4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BAZ2B — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CDC73 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DNAJA1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — HSPB1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — LONP1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MRPL4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MRPS35 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MSI2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CHAF1B — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NUP214 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — INTS9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZNF687 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SLFN5 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TBX3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MFAP1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: RANBP9 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MDN1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MIER1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ETV3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MSL3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SEPSECS — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CDK1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CALR — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MRPL41 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YPEL5 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZNF384 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — AMOTL2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBB2A — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CTNND1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ANAPC7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: DDX39A — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBA1A — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — VPRBP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — JUND (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ANAPC4 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MKLN1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MRPS22 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GLI3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ANP32A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX6 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CHD3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: KCTD5 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBA4A — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUBB8 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: FOXP4 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: IPO4 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MRPL9 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TIA1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SMC2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — AHCYL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: UBR4 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: YWHAZ — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — BAG5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MRPS9 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — PRKAR1A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BAG3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MLF2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ARID3A — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CTNNB1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ATP5A1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CBX2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SCYL2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PAF1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MED22 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — BRD8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — FOXK2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ARID5B — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TEX10 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: KPNA4 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TAF2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NAA38 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CNP — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SMG6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SRSF4 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SRP72 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — FERMT2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ANAPC5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — RBM7 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — QSER1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ILK — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — XPO5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GLIS3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MRPL39 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TNPO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: TUT1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MEIS2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: LSM3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PRKAR2B — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — LSM6 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MAEA (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CUL7 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — LEO1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — MMS19 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: EP400 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ZMYM2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CCNT1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CDC23 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ZBTB10 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: XRCC5 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — VWA9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: MTA3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — VPS33A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — THBS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — COPS3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — NOL9 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PBX2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: UBR5 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: USP24 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ZBTB7A — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SRP54 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — RBM4 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SMC3 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: USP7 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ASCC3 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — IMPDH2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PARVA — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CDK11A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: GCN1L1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — RNGTT (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: PIAS1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CORO1B — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — PPP2R5D (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: INTS7 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ZBTB5 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — CAPN2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ENOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: BRIX1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SUGP2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — TIAL1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: NOM1 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — PFKP (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SMARCA2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — ZCCHC8 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: CCAR2 — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: ANP32B — SOX2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — KCMF1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — INTS1 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SEC16A (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — EHMT2 (physical association, affinity chromatography technology)
  • IRef Biogrid Interaction: SOX2 — SET (physical association, affinity chromatography technology)
In total, 282 gene pairs are associated to this article in curated databases