Gene interactions and pathways from curated databases and text-mining
CASP3: top 25 interacting genes (chr4:185548849-185570601)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP3, not among the Top 25
Other genes interacting with CASP3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT3 ▸ XIAP ▸ IL1B ▸ FASLG ▸ MAPK3 ▸ BCL6 ▸ BCL3 ▸
BCL5 ▸ BCL9 ▸ DIABLO ▸ IL1A ▸ EPHB2 ▸ IRF6 ▸ MAPK1 ▸
MAPK12 ▸ MAPK11 ▸ MAPK14 ▸ MAPK8 ▸ MAPK10 ▸ MAPK15 ▸ MAPK9 ▸
MAPK6 ▸ MAPK7 ▸ MAPK4 ▸ MAPK13 ▸ IFNG ▸ CASP9 ▸ CASP8 ▸
APAF1 ▸ CASP12 ▸ CASP1 ▸ CASP2 ▸ CAPN1 ▸ CAPN10 ▸ DNTT ▸
CAPN5 ▸ CAPN6 ▸ CAPN7 ▸ CAPN3 ▸ CAPN13 ▸ CAPN11 ▸ CAPN2 ▸
CASP6 ▸ CAPN14 ▸ CAPN9 ▸ CAPN12 ▸ IL18 ▸ CAPN8 ▸ CAPN15 ▸
FADD ▸ CASP16 ▸ CASP10 ▸ CASP14 ▸ CASP5 ▸ CASP7 ▸ CASP4 ▸
ASIP ▸ STS ▸ MCL1 ▸ MMP2 ▸ MMP9 ▸ MMP11 ▸ MMP3 ▸
JUN ▸ MMP14 ▸ MMP12 ▸ MMP8 ▸ MMP1 ▸ MMP21 ▸ MMP26 ▸
MMP16 ▸ MMP24 ▸ MMP7 ▸ MMP17 ▸ MMP19 ▸ MMP27 ▸ MMP13 ▸
MMP25 ▸ NLRP3 ▸ MMP20 ▸ MMP10 ▸ MMP28 ▸ MMP15 ▸ CDKN1A ▸
PDCD5 ▸ PDCD11 ▸ RNF19A ▸ PDCD2 ▸ PDCD6 ▸ PDCD7 ▸ PDCD10 ▸
PDCD4 ▸ PDCD1 ▸ CFLAR ▸ CYCS ▸ NA ▸ IGF1 ▸ ANXA5 ▸
PCBD1 ▸ TGFB1 ▸ AHSA1 ▸ HLA-DRB1 ▸ MPZ ▸ PIK3CA ▸ PIK3R1 ▸
INS ▸ NLRC4 ▸ PRKCD ▸ EPO ▸ MYLIP ▸ VEGFA ▸ PI3 ▸
TAT ▸ PCNA ▸ DDIT3 ▸ IL6 ▸ NOS2 ▸ GRAP2 ▸ DFFA ▸
TNFRSF1A ▸ PRDX2 ▸ GSK3B ▸ SOD1 ▸ NGF ▸ BIRC2 ▸ IL8 ▸
DISC1 ▸ CRK ▸ DISC2 ▸ EGF ▸ PAK2 ▸ CTSB ▸ CTNNB1 ▸
EIF2AK2 ▸ IL4 ▸ PTGS2 ▸ CAST ▸ DFFB ▸ BID ▸ NOS1 ▸
LEP ▸ DNASE2 ▸ IRF1 ▸ ROCK1 ▸ FOS ▸ DNASE1 ▸ ALPI ▸
SOD2 ▸ HGF ▸ P2RX7 ▸ APP ▸ ABL1 ▸ MYC ▸ BCR ▸
CAT ▸ BDNF ▸ CTSD ▸ MAP3K1 ▸ IFI27 ▸ APEH ▸ TCF4 ▸
CDK2 ▸ IL16 ▸ IFNB1 ▸ HTRA2 ▸ PRKDC ▸ TCF3 ▸ GAL ▸
BIRC3 ▸ RAC1 ▸ NOD2 ▸ NOX1 ▸ SOD3 ▸ BMP1 ▸ TCF25 ▸
BMP4 ▸ RIPK1 ▸ BIRC7 ▸ FGF2 ▸ TCF15 ▸ TCF19 ▸ TCF21 ▸
TCF20 ▸ TCF7 ▸ TLR2 ▸ NOS3 ▸ HDAC2 ▸ IL10 ▸ TCF23 ▸
UPK3B ▸ NFKBIA ▸ TCF12 ▸ CSF2 ▸ APOB ▸ HSPA5 ▸ GZMB ▸
TCF24 ▸ IL2 ▸ ADCYAP1 ▸ POLDIP2 ▸ NOX4 ▸ NLRP1 ▸ BAD ▸
TLR4 ▸ PPARA ▸ CA2 ▸ MAGT1 ▸ CDC73 ▸ HDAC1 ▸ AIM2 ▸
ATP5O ▸ CSF3 ▸ CD8A ▸ TLR3 ▸ HMGB1 ▸ ITIH4 ▸ LMNB1 ▸
STAT1 ▸ PML ▸ MAP2K1 ▸ ARSK ▸ RAD51 ▸ RIPK2 ▸ BMP2 ▸
PDLIM7 ▸ KRT18 ▸ PPP2R1A ▸ CTR9 ▸ CD79A ▸ TLR7 ▸ IL5 ▸
BMP5 ▸ AGTR1 ▸ NOX3 ▸ PPP2CA ▸ APC ▸ ENDOG ▸ SMPD2 ▸
TLR5 ▸ BMP10 ▸ MST1 ▸ WDR61 ▸ PPP2R2B ▸ NOD1 ▸ CARD8 ▸
NOX5 ▸ HSPB1 ▸ CDK5 ▸ PAF1 ▸ LEO1 ▸ IL7 ▸ RB1 ▸
BMP3 ▸ IL3 ▸ SNAP25 ▸ STAT3 ▸ BMP7 ▸ BMP6 ▸ BMP15 ▸
IL33 ▸ IL11 ▸ HPR ▸ PRNP ▸ NPS ▸ TNFRSF1B ▸ IL20 ▸
SMARCA4 ▸ IGF2 ▸ ANGPT1 ▸ HTT ▸ ICAM1 ▸ IL24 ▸ EIF2S1 ▸
CDC6 ▸ CD4 ▸ PTX3 ▸ ARID1A ▸ GP2 ▸ ANXA1 ▸ JAK2 ▸
IL15 ▸ BIRC6 ▸ SMARCD2 ▸ ANGPT2 ▸ IL21 ▸ FOXO3 ▸ CSE ▸
ACTL6A ▸ CDH1 ▸ HIF1A ▸ CCDC88A ▸ GP6 ▸ TXN ▸ RBBP7 ▸
SYK ▸ SMARCA2 ▸ BOC ▸ TRAF6 ▸ MET ▸ CREB3 ▸ WAS ▸
LMNB2 ▸ TLR8 ▸ CREB5 ▸ MAP2K2 ▸ PTX4 ▸ EGFR ▸ SMARCE1 ▸
CXCL9 ▸ TLR10 ▸ GP5 ▸ IL25 ▸ RBBP4 ▸ SMARCC1 ▸ TLR1 ▸
SMARCD1 ▸ GP9 ▸ ABCC6 ▸ PLCG1 ▸ CREB1 ▸ RIPK3 ▸ LPA ▸
SMARCC2 ▸ PGP ▸ SMARCB1 ▸ GSN ▸ GATA1 ▸ BECN1 ▸ PAK1 ▸
MEFV ▸ IKBKB ▸ MUC1 ▸ SMPD1 ▸ PTEN ▸ IL37 ▸ ROCK2 ▸
IRF3 ▸ TLR9 ▸ MUC12 ▸ RRAS ▸ HMOX1 ▸ SYT1 ▸ RAF1 ▸
MUC22 ▸ HSPD1 ▸ MUC7 ▸ TRAF1 ▸ BRCA1 ▸ IL19 ▸ PRKCA ▸
IL31 ▸ KDR ▸ MUC4 ▸ MUC21 ▸ MSC ▸ CARD6 ▸ IL34 ▸
SP1 ▸ MUC16 ▸ RENBP ▸ MUC2 ▸ CDA ▸ MDM2 ▸ LYN ▸
IL26 ▸ IL32 ▸ MUC15 ▸ TOP1 ▸ ACHE ▸ MUC19 ▸ CDK8 ▸
STX1A ▸ CARD9 ▸ MUC8 ▸ MUC13 ▸ IL22 ▸ IL27 ▸ TLR6 ▸
CCND1 ▸ MUC20 ▸ CD79B ▸ IL13 ▸ MUC6 ▸ PLD1 ▸ MUC17 ▸
PPARG ▸ IL9 ▸ UCN ▸ CARD11 ▸ CARD16 ▸ NPM1 ▸ HIP1 ▸
LAT ▸ CEP70 ▸ MIF ▸ GRB2 ▸ CEP104 ▸ CUL1 ▸ PTHLH ▸
GUCY2D ▸ CCNH ▸ PTBP1 ▸ DES ▸ CEP350 ▸ TARDBP ▸ SLCO6A1 ▸
SETD2 ▸ IRF2 ▸ PRKAA2 ▸ CEP41 ▸ RASA1 ▸ WNT1 ▸ CEP97 ▸
FOXO1 ▸ HIST2H2BE ▸ LYPLA1 ▸ PIDD ▸ PRKAB1 ▸ SUB1 ▸ BIRC8 ▸
E2F1 ▸ PLOD2 ▸ PLD2 ▸ CTSL ▸ ARSA ▸ CEP128 ▸ PRKACG ▸
CARD18 ▸ GDNF ▸ HUNK ▸ ELAVL1 ▸ ATF5 ▸ PTK2 ▸ CDK4 ▸
CEP135 ▸ CEP55 ▸ PRKACB ▸ HSF1 ▸ SETBP1 ▸ WNK1 ▸ MAP2K5 ▸
H2AFX ▸ HSP90AA1 ▸ PPP1R3A ▸ ME2 ▸ CEP112 ▸ TRAF2 ▸ TNFRSF10A ▸
PRKAA1 ▸ CEP170 ▸ PRKAB2 ▸ CALM3 ▸ BIRC5 ▸ RAD17 ▸ GRB10 ▸
ALK ▸ PSMD10 ▸ CD47 ▸ ZGLP1 ▸ PRKCG ▸ DERL1 ▸ CEP44 ▸
PEA15 ▸ PRKAR1A ▸ GRB14 ▸ PSEN1 ▸ CEP19 ▸ PRKAR1B ▸ ATG5 ▸
CEP57 ▸ CEP76 ▸ CEP120 ▸ CEP85 ▸ CEP192 ▸ CEP250 ▸ MAP2K3 ▸
CEP72 ▸ CCR7 ▸ PNPLA2 ▸ SEC14L2 ▸ TIMP3 ▸ PRKAR2A ▸ CEP95 ▸
IRF4 ▸ MAP2K7 ▸ PRKAG1 ▸ EHMT1 ▸ PRKAR2B ▸ ATF2 ▸ SOAT1 ▸
CARD14 ▸ SLC17A5 ▸ VCP ▸ SKP1 ▸ CEP164 ▸ CEP152 ▸ TCHP ▸
CARD10 ▸ SLC9A1 ▸ BCL2L12 ▸ DST ▸ ALB ▸ IRF5 ▸ BACE1 ▸
CARD17 ▸ CEP63 ▸ VIM ▸ IKBKG ▸ EPX ▸ ARC ▸ NPY6R ▸
ADIPOQ ▸ CTNND1 ▸ CD40 ▸ PRKAG2 ▸ VDAC1 ▸ CEP68 ▸ IGF1R ▸
VIMP ▸ NTF3 ▸ FUT1 ▸ CEP89 ▸ MPST ▸ CEP290 ▸ TRAF3 ▸
GRB7 ▸ PANX1 ▸ CEP78 ▸ MAP2K4 ▸ MAP2K6 ▸ CCL2 ▸ PLD3 ▸
ANGPT4 ▸ TAC3 ▸ AIP ▸ NTF4 ▸ MT4 ▸ DHCR24 ▸ EIF4G3 ▸
STC1 ▸ IFNA2 ▸ EMP3 ▸ MED23 ▸ NUP43 ▸ BAG3 ▸ MTOR ▸
PSMB9 ▸ CDK16 ▸ EEF1A2 ▸ SERP2 ▸ MME ▸ BLM ▸ CTRL ▸
ACIN1 ▸ NLRP5 ▸ PLD5 ▸ SAA1 ▸ GPX1 ▸ LGALS1 ▸ PLD6 ▸
MTA2 ▸ IFI44 ▸ SMAD4 ▸ CDK1 ▸ VIP ▸ GYS2 ▸ AFP ▸
TNFRSF8 ▸ HTRA4 ▸ SMAD3 ▸ PRG3 ▸ CDK12 ▸ GNA11 ▸ MTA1 ▸
CCR8 ▸ CD2 ▸ NODAL ▸ HIPK2 ▸ ETS1 ▸ CPA1 ▸ LRP1 ▸
HCLS1 ▸ CDK18 ▸ DNAJC5 ▸ TGM2 ▸ MST1R ▸ APIP ▸ MED21 ▸
S100A12 ▸ PLD4 ▸ MED15 ▸ PTCH1 ▸ ACSM3 ▸ MED6 ▸ DAP3 ▸
IFIH1 ▸ FKBP4 ▸ CXCL13 ▸ PC ▸ SREBF1 ▸ MED14 ▸ LRRC59 ▸
ID3 ▸ PAN2 ▸ CIB1 ▸ CALR ▸ CENPK ▸ NANOG ▸ HDAC6 ▸
IAPP ▸ TRAF4 ▸ CALML3 ▸ GNRH1 ▸ MAP3K7 ▸ THBS1 ▸ MED1 ▸
CCNC ▸ SATB1 ▸ TSC22D3 ▸ APEX1 ▸ RAC2 ▸ NUP62 ▸ RARA ▸
TRAF5 ▸ MED7 ▸ DAPK2 ▸ IDO1 ▸ PPT1 ▸ PTH ▸ ANP32A ▸
PAWR ▸ VDAC2 ▸ RHO ▸ CCR10 ▸ GPI ▸ CCR2 ▸ KLK3 ▸
ANG ▸ NLRP7 ▸ MED25 ▸ CISH ▸ IFNA5 ▸ CDK3 ▸ DIDO1 ▸
ING1 ▸ EIF4G2 ▸ PIN1 ▸ GRP ▸ IGFBP3 ▸ GYS1 ▸ VDAC3 ▸
JAK3 ▸ DAXX ▸ QRICH1 ▸ NANOS2 ▸ CCK ▸ APOBEC3D ▸ SREBF2 ▸
PRG2 ▸ KLF4 ▸ RAD18 ▸ SERPINA1 ▸ MED26 ▸ PARG ▸ QRICH2 ▸
FAF1 ▸ EMP1 ▸ NR0B1 ▸ HMGCR ▸ PGF ▸ SERPINF1 ▸ TNFSF12 ▸
NUAK1 ▸ TMED7 ▸ SHH ▸ TRA ▸ CDK14 ▸ TRAF7 ▸ NLRC5 ▸
CDC42 ▸ PLK1 ▸ NTN1 ▸ E2F2 ▸ FAM168B ▸ ABCD1 ▸ CCR4 ▸
TAC1 ▸ CDK15 ▸ RBL2 ▸ IRF7 ▸ CALB1 ▸ IRF9 ▸ SHC1 ▸
ADH5 ▸ MED24 ▸ COP ▸ CFL1 ▸ NPPA ▸ CCR3 ▸ NAB1 ▸
CAPNS1 ▸ ITCH ▸ CCL19 ▸ ETS2 ▸ CPOX ▸ WNT3A ▸ MTA3 ▸
KMT2A ▸ CHUK ▸ ODC1 ▸ RAC3 ▸ RIPK4 ▸ RUNX3 ▸ HDAC4 ▸
MAP2 ▸ IRF8 ▸ SEPT4 ▸ CDK19 ▸ GSTT1 ▸ SPP1 ▸ CCR5 ▸
CDK6 ▸ TET2 ▸ NACA ▸ MED4 ▸ DYRK1A ▸ CCR9 ▸ JAK1 ▸
EIF4G1 ▸ TET3 ▸ GLI1 ▸ CDK20 ▸ STX2 ▸ TNFRSF10B ▸ NOTCH1 ▸
IRS1 ▸ RAD1 ▸ CCR1 ▸ NUP210 ▸ KLKB1 ▸ EDNRA ▸ PTPN11 ▸
PXN ▸ CDK9 ▸ GHSR ▸ ADM ▸ CSF1 ▸ GPX3 ▸ HTRA1 ▸
HRK ▸ CCR6 ▸ DLG1 ▸ BNIP3 ▸ CDCA5 ▸ MTX1 ▸ MED12 ▸
RAD50 ▸ TGFB3 ▸ CA8 ▸ CD8B ▸ IL1RN ▸ TFAP2A ▸ CDK13 ▸
CDK17 ▸ ACR ▸ CFTR ▸ PAN3 ▸ CDK10 ▸ APOE ▸ MED13 ▸
ANXA6 ▸ MED17 ▸ CTNNBL1 ▸ MT3 ▸ HRD ▸ SERPINB9 ▸ MED8 ▸
RAD52 ▸ ACAD8 ▸ TYR ▸ NUP214 ▸ SMAD7 ▸ PMEL ▸ BCAP31 ▸
PSENEN ▸ CRYAB ▸ ERVK-6 ▸ STSP1 ▸ PAEP ▸ FHIT ▸ MICE ▸
CDK7 ▸ FLT3 ▸ E2F3 ▸ NAIP ▸ EMP2 ▸ C22orf29 ▸ XRCC6 ▸
XAF1 ▸ ATG3 ▸ PDGFB ▸ SLPI ▸ EML2 ▸ TET1 ▸ ATM ▸
NUP153 ▸ UCP2 ▸ PRG4 ▸ NAB2 ▸ GJA1 ▸ CYR61 ▸ TAC4 ▸
SIVA1 ▸ SDS ▸ RAD21 ▸ HTRA3 ▸ ARHGDIA ▸ KARS ▸ GAS2 ▸
NFATC2 ▸ SDC2 ▸ MAPK8IP3 ▸ MDC1 ▸ SOCS5 ▸ SCAF11 ▸ DBNL ▸
EIF4A1 ▸ RABEP1 ▸ LPAR1 ▸ DCTN1 ▸ YWHAE ▸ PLA2G4B ▸ NUCB2 ▸
CDC2L1 ▸ HNRNPA0 ▸ ELANE ▸ TP73 ▸ NGFRAP1 ▸ ACTA1 ▸ NVL ▸
IL1R2 ▸ NGFR ▸ NEO1 ▸ CDK11A ▸ EIF4B ▸ AKAP8 ▸ GZMM ▸
CAD ▸ BMX ▸ PSIP1 ▸ RBX1 ▸ TRIM28 ▸ NFE2L2 ▸ SAV1 ▸
UNC5B ▸ DSG2 ▸ ARHGDIB ▸ FBXW11 ▸ FUS ▸ NR3C1 ▸ MEF2A ▸
CDK11B ▸ TNS4 ▸ PLA2G4A ▸ ATG4D ▸ NDUFS1 ▸ PPARGC1A ▸ SYF2 ▸
MAP3K14 ▸ YWHAG ▸ IL1R1 ▸ GORASP1 ▸ PTMA ▸ MAP4K1 ▸ PDE10A ▸
IQGAP1 ▸ TNFRSF25 ▸ BCAR1 ▸ COPS6 ▸ PIP5K1A ▸ KEAP1 ▸ CD247 ▸
MAPT ▸ HRAS ▸ PLEKHO1 ▸ IFT57 ▸ NUMA1 ▸ DSG3 ▸ EIF3J ▸
LPAR3 ▸ PTGES3 ▸ THAP11 ▸ AIFM1 ▸ MLH1 ▸ CDC2L2 ▸ GRIPAP1 ▸
ACVR1C ▸ UBC ▸ NMT2 ▸ AR ▸ ATN1 ▸ HEY2 ▸ HNRNPD ▸
HNRNPU ▸ UBE4B ▸ WNK3 ▸ DSG1 ▸ RNF2 ▸ PPP3CA ▸ PRF1 ▸
PDE5A ▸ ZBTB16 ▸ CTTN ▸ SARS2 ▸ BIRC4 ▸ EIF3S10 ▸ FUK ▸
PICALM ▸ GMNN ▸ STK24 ▸
Data information
Please see the Gene Interactions Track Manual.