Gene interactions and pathways from curated databases and text-mining
CASP3: top 25 interacting genes (chr4:185548849-185570601)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP3, not among the Top 25
Other genes interacting with CASP3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT3 ▸ XIAP ▸ IL1B ▸ FASLG ▸ MAPK3 ▸ IL1A ▸ BCL5 ▸
DIABLO ▸ BCL6 ▸ BCL9 ▸ BCL3 ▸ EPHB2 ▸ IRF6 ▸ MAPK1 ▸
MAPK14 ▸ MAPK15 ▸ MAPK6 ▸ MAPK11 ▸ MAPK8 ▸ MAPK10 ▸ MAPK13 ▸
MAPK12 ▸ MAPK4 ▸ MAPK7 ▸ MAPK9 ▸ IFNG ▸ CASP9 ▸ CASP8 ▸
APAF1 ▸ CASP12 ▸ CASP1 ▸ CASP2 ▸ CAPN1 ▸ CAPN10 ▸ DNTT ▸
CAPN9 ▸ CAPN7 ▸ CAPN8 ▸ CAPN12 ▸ CAPN15 ▸ IL18 ▸ CAPN2 ▸
CAPN3 ▸ CAPN11 ▸ CAPN5 ▸ CAPN14 ▸ CAPN13 ▸ CAPN6 ▸ CASP6 ▸
FADD ▸ CASP16 ▸ CASP7 ▸ CASP10 ▸ CASP5 ▸ CASP14 ▸ CASP4 ▸
STS ▸ ASIP ▸ MCL1 ▸ MMP2 ▸ MMP9 ▸ JUN ▸ MMP3 ▸
MMP14 ▸ MMP12 ▸ MMP11 ▸ MMP15 ▸ MMP10 ▸ MMP21 ▸ MMP16 ▸
MMP8 ▸ CDKN1A ▸ MMP26 ▸ MMP13 ▸ MMP25 ▸ MMP17 ▸ MMP28 ▸
MMP20 ▸ MMP24 ▸ MMP1 ▸ NLRP3 ▸ MMP7 ▸ MMP27 ▸ MMP19 ▸
PDCD11 ▸ PDCD5 ▸ PDCD2 ▸ PDCD6 ▸ PDCD1 ▸ PDCD10 ▸ PDCD4 ▸
PDCD7 ▸ RNF19A ▸ CYCS ▸ CFLAR ▸ NA ▸ IGF1 ▸ PCBD1 ▸
ANXA5 ▸ TGFB1 ▸ AHSA1 ▸ PIK3CA ▸ MPZ ▸ INS ▸ PIK3R1 ▸
HLA-DRB1 ▸ EPO ▸ NLRC4 ▸ PRKCD ▸ VEGFA ▸ PI3 ▸ MYLIP ▸
IL6 ▸ TAT ▸ DDIT3 ▸ PCNA ▸ DFFA ▸ NOS2 ▸ GRAP2 ▸
GSK3B ▸ PRDX2 ▸ TNFRSF1A ▸ EGF ▸ PAK2 ▸ CRK ▸ NGF ▸
BIRC2 ▸ CTSB ▸ DISC1 ▸ DISC2 ▸ IL8 ▸ SOD1 ▸ EIF2AK2 ▸
PTGS2 ▸ CAST ▸ CTNNB1 ▸ IL4 ▸ NOS1 ▸ BID ▸ DFFB ▸
LEP ▸ P2RX7 ▸ ABL1 ▸ SOD2 ▸ APP ▸ FOS ▸ MYC ▸
IRF1 ▸ HGF ▸ ROCK1 ▸ DNASE2 ▸ DNASE1 ▸ ALPI ▸ IL16 ▸
CDK2 ▸ MAP3K1 ▸ APEH ▸ TCF4 ▸ CTSD ▸ IFI27 ▸ IFNB1 ▸
BCR ▸ CAT ▸ HTRA2 ▸ BDNF ▸ APOB ▸ BIRC3 ▸ SOD3 ▸
TCF19 ▸ TCF15 ▸ PRKDC ▸ RIPK1 ▸ TCF25 ▸ NOS3 ▸ TCF3 ▸
GZMB ▸ RAC1 ▸ TLR2 ▸ BMP4 ▸ HSPA5 ▸ TCF23 ▸ CSF2 ▸
BMP1 ▸ GAL ▸ TCF24 ▸ TCF7 ▸ IL10 ▸ HDAC2 ▸ TCF12 ▸
TCF20 ▸ NFKBIA ▸ NOX1 ▸ NOD2 ▸ TCF21 ▸ FGF2 ▸ BIRC7 ▸
UPK3B ▸ HDAC1 ▸ TLR3 ▸ PML ▸ POLDIP2 ▸ NOX4 ▸ ARSK ▸
CD8A ▸ NLRP1 ▸ STAT1 ▸ CA2 ▸ AIM2 ▸ HMGB1 ▸ MAP2K1 ▸
CDC73 ▸ ADCYAP1 ▸ PPARA ▸ BAD ▸ ATP5O ▸ IL2 ▸ ITIH4 ▸
LMNB1 ▸ MAGT1 ▸ TLR4 ▸ CSF3 ▸ NOD1 ▸ STAT3 ▸ TLR7 ▸
RAD51 ▸ IL7 ▸ AGTR1 ▸ HPR ▸ NOX3 ▸ CTR9 ▸ PDLIM7 ▸
IL3 ▸ IL33 ▸ IL5 ▸ PAF1 ▸ NOX5 ▸ TLR5 ▸ BMP5 ▸
BMP10 ▸ BMP2 ▸ SMPD2 ▸ RB1 ▸ PPP2CA ▸ ENDOG ▸ KRT18 ▸
PRNP ▸ LEO1 ▸ PPP2R1A ▸ MST1 ▸ BMP15 ▸ IL11 ▸ BMP6 ▸
SNAP25 ▸ RIPK2 ▸ CDK5 ▸ CARD8 ▸ PPP2R2B ▸ BMP7 ▸ BMP3 ▸
CD79A ▸ HSPB1 ▸ WDR61 ▸ APC ▸ ABCC6 ▸ IL21 ▸ PTX4 ▸
MET ▸ TRAF6 ▸ MAP2K2 ▸ TLR1 ▸ HTT ▸ BIRC6 ▸ SYK ▸
SMARCA4 ▸ ARID1A ▸ IGF2 ▸ GP2 ▸ SMARCA2 ▸ SMARCE1 ▸ RBBP4 ▸
HIF1A ▸ PGP ▸ ANGPT1 ▸ IL20 ▸ ANGPT2 ▸ ANXA1 ▸ CREB3 ▸
CREB5 ▸ LPA ▸ GP9 ▸ TXN ▸ CXCL9 ▸ BOC ▸ RIPK3 ▸
GP6 ▸ LMNB2 ▸ SMARCB1 ▸ IL24 ▸ PLCG1 ▸ CDH1 ▸ JAK2 ▸
RBBP7 ▸ ACTL6A ▸ SMARCC2 ▸ IL25 ▸ CDC6 ▸ TLR8 ▸ SMARCD2 ▸
CSE ▸ ICAM1 ▸ CD4 ▸ IL15 ▸ NPS ▸ GSN ▸ WAS ▸
GP5 ▸ SMARCD1 ▸ CREB1 ▸ PTX3 ▸ TLR10 ▸ CCDC88A ▸ EGFR ▸
TNFRSF1B ▸ FOXO3 ▸ EIF2S1 ▸ SMARCC1 ▸ IKBKB ▸ BECN1 ▸ ROCK2 ▸
IL31 ▸ IL26 ▸ CARD6 ▸ CDA ▸ MUC22 ▸ IL32 ▸ CCND1 ▸
TOP1 ▸ IL22 ▸ CDK8 ▸ GATA1 ▸ SYT1 ▸ TLR6 ▸ IL19 ▸
MUC2 ▸ MUC12 ▸ KDR ▸ LYN ▸ MDM2 ▸ SP1 ▸ MEFV ▸
MUC19 ▸ MUC13 ▸ MUC6 ▸ IRF3 ▸ MUC15 ▸ PPARG ▸ MUC17 ▸
BRCA1 ▸ MUC4 ▸ UCN ▸ MUC1 ▸ TLR9 ▸ ACHE ▸ IL9 ▸
MSC ▸ STX1A ▸ MUC16 ▸ CARD11 ▸ MUC7 ▸ RENBP ▸ PRKCA ▸
SMPD1 ▸ PLD1 ▸ PTEN ▸ CARD9 ▸ IL13 ▸ RRAS ▸ MUC21 ▸
RAF1 ▸ IL37 ▸ PAK1 ▸ MUC20 ▸ TRAF1 ▸ MUC8 ▸ IL34 ▸
HSPD1 ▸ CD79B ▸ IL27 ▸ HMOX1 ▸ RASA1 ▸ ELAVL1 ▸ IKBKG ▸
PRKAA2 ▸ ALK ▸ ATF2 ▸ CEP290 ▸ PPP1R3A ▸ LAT ▸ PTBP1 ▸
CEP128 ▸ IGF1R ▸ MIF ▸ SETBP1 ▸ VIM ▸ RAD17 ▸ PRKAR1A ▸
GDNF ▸ SLC17A5 ▸ CARD18 ▸ IRF2 ▸ NPY6R ▸ CEP78 ▸ ME2 ▸
BACE1 ▸ CARD10 ▸ GRB10 ▸ LYPLA1 ▸ NPM1 ▸ PRKAB1 ▸ PEA15 ▸
HSP90AA1 ▸ ZGLP1 ▸ SETD2 ▸ CEP250 ▸ ALB ▸ CEP164 ▸ FOXO1 ▸
CEP41 ▸ MAP2K6 ▸ TRAF2 ▸ ARSA ▸ CD40 ▸ BIRC8 ▸ PLOD2 ▸
PIDD ▸ CEP89 ▸ CD47 ▸ PRKAA1 ▸ CARD16 ▸ CEP85 ▸ PSEN1 ▸
E2F1 ▸ CEP104 ▸ PNPLA2 ▸ EPX ▸ TNFRSF10A ▸ GRB7 ▸ MAP2K3 ▸
CARD14 ▸ IRF5 ▸ PSMD10 ▸ CTNND1 ▸ HUNK ▸ VIMP ▸ BIRC5 ▸
PLD2 ▸ CCNH ▸ MPST ▸ CEP68 ▸ CEP44 ▸ HSF1 ▸ CEP76 ▸
NTF3 ▸ PANX1 ▸ HIST2H2BE ▸ DERL1 ▸ ADIPOQ ▸ PRKAB2 ▸ PTHLH ▸
WNT1 ▸ CDK4 ▸ EHMT1 ▸ CEP350 ▸ CEP55 ▸ CEP70 ▸ CEP57 ▸
PRKCG ▸ ARC ▸ GRB2 ▸ TRAF3 ▸ CEP112 ▸ PRKAR2B ▸ WNK1 ▸
CCL2 ▸ CEP72 ▸ SLCO6A1 ▸ PRKACB ▸ CEP63 ▸ DES ▸ GUCY2D ▸
CEP170 ▸ TIMP3 ▸ TARDBP ▸ TCHP ▸ CEP135 ▸ PRKAR2A ▸ ATF5 ▸
PRKAG1 ▸ HIP1 ▸ CARD17 ▸ CCR7 ▸ SUB1 ▸ ATG5 ▸ PRKAR1B ▸
CEP95 ▸ VDAC1 ▸ CALM3 ▸ PRKAG2 ▸ CTSL ▸ CEP120 ▸ SLC9A1 ▸
DST ▸ VCP ▸ PTK2 ▸ IRF4 ▸ MAP2K5 ▸ SKP1 ▸ H2AFX ▸
MAP2K4 ▸ BCL2L12 ▸ GRB14 ▸ PRKACG ▸ CUL1 ▸ FUT1 ▸ CEP192 ▸
SEC14L2 ▸ CEP19 ▸ MAP2K7 ▸ CEP97 ▸ CEP152 ▸ SOAT1 ▸ ID3 ▸
CDK6 ▸ RAD18 ▸ NR0B1 ▸ CCR10 ▸ DAPK2 ▸ SAA1 ▸ MAP2 ▸
ANGPT4 ▸ APIP ▸ IL1RN ▸ CCR5 ▸ CISH ▸ MTOR ▸ TMED7 ▸
PPT1 ▸ HTRA1 ▸ EEF1A2 ▸ JAK3 ▸ NANOS2 ▸ MTA3 ▸ ITCH ▸
PAN3 ▸ SERPINA1 ▸ CD2 ▸ XRCC6 ▸ DHCR24 ▸ SHH ▸ CALB1 ▸
CDK9 ▸ ACAD8 ▸ MED1 ▸ VIP ▸ PRG4 ▸ IFNA2 ▸ IRF7 ▸
CDK13 ▸ ANXA6 ▸ RIPK4 ▸ PLD5 ▸ CDK19 ▸ TET2 ▸ PLD6 ▸
DAP3 ▸ CDK12 ▸ BNIP3 ▸ ANP32A ▸ MED14 ▸ CFTR ▸ CA8 ▸
NOTCH1 ▸ RAD21 ▸ ADH5 ▸ CCR3 ▸ MT3 ▸ PTCH1 ▸ NLRC5 ▸
CCR1 ▸ FKBP4 ▸ NTF4 ▸ PARG ▸ NAB1 ▸ RAD1 ▸ QRICH2 ▸
PTH ▸ ACR ▸ SMAD4 ▸ FAM168B ▸ ODC1 ▸ BAG3 ▸ IRS1 ▸
TNFRSF10B ▸ LRRC59 ▸ HDAC6 ▸ HTRA4 ▸ TRA ▸ IRF9 ▸ CCR8 ▸
GYS1 ▸ TGFB3 ▸ PXN ▸ MTX1 ▸ MICE ▸ GLI1 ▸ PAEP ▸
NANOG ▸ MED24 ▸ MT4 ▸ PRG2 ▸ APEX1 ▸ IFIH1 ▸ NLRP5 ▸
TSC22D3 ▸ NUP210 ▸ PSMB9 ▸ CCR2 ▸ HMGCR ▸ AIP ▸ TAC1 ▸
CXCL13 ▸ MED13 ▸ EIF4G1 ▸ SREBF1 ▸ MTA2 ▸ S100A12 ▸ TAC4 ▸
PLK1 ▸ PAN2 ▸ SEPT4 ▸ HCLS1 ▸ RAD52 ▸ NACA ▸ CRYAB ▸
SHC1 ▸ DYRK1A ▸ EML2 ▸ NAIP ▸ RAC3 ▸ GNA11 ▸ CTNNBL1 ▸
CDK20 ▸ QRICH1 ▸ CDC42 ▸ SIVA1 ▸ PMEL ▸ NTN1 ▸ CDK1 ▸
GYS2 ▸ TFAP2A ▸ SERPINB9 ▸ ACSM3 ▸ C22orf29 ▸ CIB1 ▸ BLM ▸
TAC3 ▸ CYR61 ▸ SMAD7 ▸ CDCA5 ▸ THBS1 ▸ PRG3 ▸ TYR ▸
TRAF4 ▸ NUP214 ▸ HDAC4 ▸ EMP3 ▸ GPX1 ▸ IAPP ▸ TET1 ▸
SPP1 ▸ EIF4G3 ▸ FHIT ▸ ABCD1 ▸ E2F2 ▸ KMT2A ▸ CDK15 ▸
ADM ▸ XAF1 ▸ RAC2 ▸ ERVK-6 ▸ CDK3 ▸ ING1 ▸ TRAF7 ▸
LGALS1 ▸ IRF8 ▸ PSENEN ▸ MED26 ▸ HTRA3 ▸ ETS1 ▸ CALML3 ▸
HRK ▸ TGM2 ▸ TNFSF12 ▸ STSP1 ▸ CALR ▸ SDS ▸ APOBEC3D ▸
NUAK1 ▸ HRD ▸ CCL19 ▸ CENPK ▸ SREBF2 ▸ CHUK ▸ MED4 ▸
CDK18 ▸ RBL2 ▸ BCAP31 ▸ MED15 ▸ MED6 ▸ TRAF5 ▸ NLRP7 ▸
MED23 ▸ GPX3 ▸ DAXX ▸ E2F3 ▸ MED17 ▸ CCR4 ▸ VDAC3 ▸
MED7 ▸ ETS2 ▸ SATB1 ▸ ACIN1 ▸ EIF4G2 ▸ RAD50 ▸ NPPA ▸
NUP153 ▸ CDK14 ▸ IFNA5 ▸ GNRH1 ▸ CPOX ▸ GHSR ▸ SERPINF1 ▸
FAF1 ▸ CSF1 ▸ MME ▸ CCNC ▸ CDK16 ▸ GJA1 ▸ EDNRA ▸
ATM ▸ EMP1 ▸ IGFBP3 ▸ ATG3 ▸ WNT3A ▸ MAP3K7 ▸ RHO ▸
STC1 ▸ PLD4 ▸ GSTT1 ▸ MST1R ▸ KLKB1 ▸ CCK ▸ CTRL ▸
GPI ▸ CCR6 ▸ COP ▸ NODAL ▸ DLG1 ▸ IFI44 ▸ APOE ▸
TET3 ▸ CPA1 ▸ SLPI ▸ TNFRSF8 ▸ IDO1 ▸ KLF4 ▸ LRP1 ▸
MED12 ▸ MTA1 ▸ PGF ▸ CAPNS1 ▸ HIPK2 ▸ NAB2 ▸ EMP2 ▸
PC ▸ DIDO1 ▸ NUP62 ▸ PIN1 ▸ CDK10 ▸ GRP ▸ CDK7 ▸
RUNX3 ▸ PDGFB ▸ KLK3 ▸ PTPN11 ▸ VDAC2 ▸ RARA ▸ CFL1 ▸
JAK1 ▸ PAWR ▸ SERP2 ▸ AFP ▸ FLT3 ▸ CDK17 ▸ MED21 ▸
STX2 ▸ PLD3 ▸ CCR9 ▸ UCP2 ▸ MED25 ▸ MED8 ▸ DNAJC5 ▸
CD8B ▸ NUP43 ▸ SMAD3 ▸ ANG ▸ YWHAG ▸ NFATC2 ▸ BMX ▸
CDK11A ▸ NFE2L2 ▸ PSIP1 ▸ RBX1 ▸ HNRNPA0 ▸ IQGAP1 ▸ FUK ▸
BCAR1 ▸ GRIPAP1 ▸ IL1R2 ▸ EIF3J ▸ SOCS5 ▸ COPS6 ▸ PPP3CA ▸
NUMA1 ▸ RABEP1 ▸ MLH1 ▸ UBC ▸ DCTN1 ▸ LPAR1 ▸ YWHAE ▸
CD247 ▸ MAPT ▸ ARHGDIA ▸ PIP5K1A ▸ EIF4A1 ▸ TRIM28 ▸ MDC1 ▸
NVL ▸ GAS2 ▸ ATN1 ▸ CDC2L1 ▸ SARS2 ▸ TP73 ▸ RNF2 ▸
NMT2 ▸ PRF1 ▸ DSG2 ▸ SAV1 ▸ ACVR1C ▸ NGFR ▸ MEF2A ▸
PDE10A ▸ HNRNPD ▸ PLA2G4B ▸ SDC2 ▸ EIF3S10 ▸ CDC2L2 ▸ SYF2 ▸
THAP11 ▸ CDK11B ▸ MAPK8IP3 ▸ STK24 ▸ CAD ▸ GMNN ▸ SCAF11 ▸
AIFM1 ▸ NDUFS1 ▸ WNK3 ▸ TNS4 ▸ PLEKHO1 ▸ NEO1 ▸ PLA2G4A ▸
GZMM ▸ FUS ▸ AR ▸ HNRNPU ▸ ELANE ▸ LPAR3 ▸ PPARGC1A ▸
HRAS ▸ DBNL ▸ UBE4B ▸ PTMA ▸ TNFRSF25 ▸ BIRC4 ▸ GORASP1 ▸
IL1R1 ▸ DSG1 ▸ ARHGDIB ▸ ZBTB16 ▸ PICALM ▸ AKAP8 ▸ IFT57 ▸
ATG4D ▸ KARS ▸ CTTN ▸ DSG3 ▸ NUCB2 ▸ MAP3K14 ▸ PDE5A ▸
PTGES3 ▸ KEAP1 ▸ MAP4K1 ▸ UNC5B ▸ NR3C1 ▸ HEY2 ▸ EIF4B ▸
NGFRAP1 ▸ ACTA1 ▸ FBXW11 ▸
Data information
Please see the Gene Interactions Track Manual.