Gene interactions and pathways from curated databases and text-mining
CASP3: top 25 interacting genes (chr4:185548849-185570601)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP3, not among the Top 25
Other genes interacting with CASP3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT3 ▸ XIAP ▸ IL1B ▸ FASLG ▸ MAPK3 ▸ BCL3 ▸ BCL5 ▸
DIABLO ▸ BCL6 ▸ BCL9 ▸ IL1A ▸ EPHB2 ▸ IRF6 ▸ MAPK1 ▸
MAPK10 ▸ MAPK14 ▸ MAPK7 ▸ MAPK6 ▸ MAPK9 ▸ MAPK8 ▸ MAPK4 ▸
MAPK12 ▸ MAPK11 ▸ MAPK15 ▸ MAPK13 ▸ IFNG ▸ CASP9 ▸ CASP8 ▸
APAF1 ▸ CASP12 ▸ CASP1 ▸ CASP2 ▸ CAPN1 ▸ DNTT ▸ CAPN10 ▸
CAPN14 ▸ CAPN11 ▸ CAPN7 ▸ IL18 ▸ CAPN15 ▸ CASP6 ▸ CAPN2 ▸
CAPN6 ▸ CAPN13 ▸ CAPN8 ▸ CAPN3 ▸ CAPN12 ▸ CAPN9 ▸ CAPN5 ▸
FADD ▸ CASP5 ▸ CASP16 ▸ CASP14 ▸ CASP7 ▸ CASP4 ▸ CASP10 ▸
ASIP ▸ STS ▸ MCL1 ▸ MMP2 ▸ MMP9 ▸ MMP11 ▸ MMP12 ▸
MMP14 ▸ MMP3 ▸ JUN ▸ MMP16 ▸ MMP24 ▸ MMP13 ▸ NLRP3 ▸
CDKN1A ▸ MMP8 ▸ MMP10 ▸ MMP28 ▸ MMP1 ▸ MMP7 ▸ MMP15 ▸
MMP27 ▸ MMP19 ▸ MMP21 ▸ MMP20 ▸ MMP25 ▸ MMP26 ▸ MMP17 ▸
PDCD5 ▸ PDCD11 ▸ PDCD10 ▸ PDCD1 ▸ PDCD7 ▸ PDCD2 ▸ RNF19A ▸
PDCD6 ▸ PDCD4 ▸ CYCS ▸ CFLAR ▸ NA ▸ IGF1 ▸ PCBD1 ▸
ANXA5 ▸ TGFB1 ▸ AHSA1 ▸ MPZ ▸ INS ▸ HLA-DRB1 ▸ PIK3CA ▸
PIK3R1 ▸ EPO ▸ PRKCD ▸ NLRC4 ▸ MYLIP ▸ VEGFA ▸ PI3 ▸
IL6 ▸ DDIT3 ▸ PCNA ▸ TAT ▸ DFFA ▸ GRAP2 ▸ NOS2 ▸
TNFRSF1A ▸ PRDX2 ▸ GSK3B ▸ CTSB ▸ EGF ▸ DISC2 ▸ PAK2 ▸
IL8 ▸ NGF ▸ CRK ▸ DISC1 ▸ SOD1 ▸ BIRC2 ▸ PTGS2 ▸
EIF2AK2 ▸ CAST ▸ IL4 ▸ CTNNB1 ▸ DFFB ▸ LEP ▸ BID ▸
NOS1 ▸ DNASE2 ▸ MYC ▸ HGF ▸ IRF1 ▸ ROCK1 ▸ FOS ▸
SOD2 ▸ APP ▸ DNASE1 ▸ ALPI ▸ P2RX7 ▸ ABL1 ▸ APEH ▸
CAT ▸ IFNB1 ▸ CDK2 ▸ HTRA2 ▸ BDNF ▸ TCF4 ▸ IL16 ▸
CTSD ▸ MAP3K1 ▸ BCR ▸ IFI27 ▸ NOX1 ▸ TCF19 ▸ TCF23 ▸
GAL ▸ NOD2 ▸ NOS3 ▸ HSPA5 ▸ PRKDC ▸ FGF2 ▸ NFKBIA ▸
SOD3 ▸ UPK3B ▸ RIPK1 ▸ BMP1 ▸ BMP4 ▸ TCF20 ▸ IL10 ▸
BIRC7 ▸ TCF24 ▸ TCF25 ▸ TCF15 ▸ GZMB ▸ TCF3 ▸ TLR2 ▸
HDAC2 ▸ BIRC3 ▸ TCF21 ▸ TCF12 ▸ RAC1 ▸ CSF2 ▸ TCF7 ▸
APOB ▸ PML ▸ PPARA ▸ CSF3 ▸ MAGT1 ▸ ITIH4 ▸ HMGB1 ▸
BAD ▸ CD8A ▸ STAT1 ▸ CA2 ▸ AIM2 ▸ ATP5O ▸ MAP2K1 ▸
TLR3 ▸ CDC73 ▸ POLDIP2 ▸ ARSK ▸ HDAC1 ▸ LMNB1 ▸ ADCYAP1 ▸
IL2 ▸ NLRP1 ▸ NOX4 ▸ TLR4 ▸ PAF1 ▸ HSPB1 ▸ IL3 ▸
RB1 ▸ CD79A ▸ HPR ▸ MST1 ▸ NOX3 ▸ SNAP25 ▸ PPP2R2B ▸
PRNP ▸ BMP15 ▸ CDK5 ▸ TLR7 ▸ BMP5 ▸ IL5 ▸ BMP10 ▸
WDR61 ▸ IL11 ▸ KRT18 ▸ NOX5 ▸ AGTR1 ▸ SMPD2 ▸ PDLIM7 ▸
STAT3 ▸ BMP3 ▸ RAD51 ▸ TLR5 ▸ CTR9 ▸ BMP7 ▸ PPP2R1A ▸
NOD1 ▸ BMP2 ▸ LEO1 ▸ APC ▸ RIPK2 ▸ ENDOG ▸ BMP6 ▸
IL33 ▸ IL7 ▸ CARD8 ▸ PPP2CA ▸ NPS ▸ WAS ▸ SYK ▸
SMARCD1 ▸ TXN ▸ MAP2K2 ▸ GP2 ▸ IL25 ▸ PGP ▸ SMARCB1 ▸
PTX4 ▸ SMARCE1 ▸ TLR8 ▸ PLCG1 ▸ ANXA1 ▸ TNFRSF1B ▸ CREB3 ▸
BIRC6 ▸ ANGPT1 ▸ GP6 ▸ ANGPT2 ▸ SMARCC2 ▸ CXCL9 ▸ CREB5 ▸
CDC6 ▸ LPA ▸ RIPK3 ▸ JAK2 ▸ EGFR ▸ IL20 ▸ ICAM1 ▸
ACTL6A ▸ CSE ▸ SMARCA2 ▸ PTX3 ▸ SMARCC1 ▸ CD4 ▸ ARID1A ▸
HTT ▸ CDH1 ▸ IL15 ▸ TLR1 ▸ CREB1 ▸ BOC ▸ GP5 ▸
RBBP7 ▸ MET ▸ EIF2S1 ▸ TRAF6 ▸ GP9 ▸ TLR10 ▸ IGF2 ▸
IL21 ▸ LMNB2 ▸ GSN ▸ HIF1A ▸ RBBP4 ▸ CCDC88A ▸ ABCC6 ▸
SMARCA4 ▸ SMARCD2 ▸ FOXO3 ▸ IL24 ▸ HMOX1 ▸ IL9 ▸ HSPD1 ▸
CCND1 ▸ IL13 ▸ MUC19 ▸ SYT1 ▸ MUC20 ▸ TRAF1 ▸ RAF1 ▸
PTEN ▸ IL32 ▸ MUC1 ▸ TOP1 ▸ MDM2 ▸ RENBP ▸ MUC21 ▸
MUC7 ▸ MUC12 ▸ TLR9 ▸ MUC6 ▸ IL19 ▸ SP1 ▸ CDK8 ▸
CARD9 ▸ MUC2 ▸ RRAS ▸ MUC4 ▸ PRKCA ▸ PAK1 ▸ IL34 ▸
SMPD1 ▸ MUC17 ▸ BECN1 ▸ MSC ▸ TLR6 ▸ PPARG ▸ CARD6 ▸
MEFV ▸ MUC15 ▸ MUC16 ▸ CD79B ▸ IL37 ▸ MUC22 ▸ IL26 ▸
IL27 ▸ CDA ▸ CARD11 ▸ IL22 ▸ ACHE ▸ MUC8 ▸ LYN ▸
ROCK2 ▸ MUC13 ▸ IKBKB ▸ IL31 ▸ GATA1 ▸ STX1A ▸ BRCA1 ▸
IRF3 ▸ KDR ▸ PLD1 ▸ UCN ▸ E2F1 ▸ ATF2 ▸ BIRC8 ▸
TRAF2 ▸ CUL1 ▸ PRKAA2 ▸ CEP97 ▸ PRKAR1A ▸ MAP2K3 ▸ PSMD10 ▸
HUNK ▸ ATF5 ▸ BCL2L12 ▸ ZGLP1 ▸ PPP1R3A ▸ SLC9A1 ▸ HIST2H2BE ▸
PRKACB ▸ RASA1 ▸ PRKAR1B ▸ PRKAR2B ▸ HSP90AA1 ▸ ATG5 ▸ ME2 ▸
MAP2K7 ▸ GRB7 ▸ FOXO1 ▸ EPX ▸ TARDBP ▸ CEP63 ▸ LYPLA1 ▸
BIRC5 ▸ SETBP1 ▸ LAT ▸ ADIPOQ ▸ ALK ▸ WNK1 ▸ PLD2 ▸
CEP44 ▸ CALM3 ▸ CTSL ▸ HIP1 ▸ NPM1 ▸ CEP350 ▸ PRKAB1 ▸
CEP78 ▸ CEP41 ▸ CEP135 ▸ TNFRSF10A ▸ PNPLA2 ▸ SEC14L2 ▸ CCNH ▸
CEP250 ▸ FUT1 ▸ CARD17 ▸ CEP57 ▸ CEP85 ▸ PIDD ▸ MAP2K4 ▸
TIMP3 ▸ VIM ▸ SOAT1 ▸ VDAC1 ▸ GRB10 ▸ H2AFX ▸ TRAF3 ▸
PRKAA1 ▸ VCP ▸ CEP192 ▸ DES ▸ CARD14 ▸ PRKAG2 ▸ SKP1 ▸
SUB1 ▸ GRB2 ▸ PRKAR2A ▸ PRKACG ▸ SLCO6A1 ▸ PTHLH ▸ CEP76 ▸
CEP112 ▸ IRF2 ▸ MAP2K5 ▸ PLOD2 ▸ CD40 ▸ EHMT1 ▸ PANX1 ▸
PRKAG1 ▸ CEP290 ▸ PEA15 ▸ CD47 ▸ DST ▸ HSF1 ▸ CARD18 ▸
CEP19 ▸ IRF5 ▸ TCHP ▸ CARD10 ▸ IKBKG ▸ MAP2K6 ▸ MPST ▸
VIMP ▸ RAD17 ▸ SETD2 ▸ ALB ▸ GRB14 ▸ CEP120 ▸ CEP72 ▸
CCR7 ▸ CEP152 ▸ PTBP1 ▸ GUCY2D ▸ CEP70 ▸ BACE1 ▸ GDNF ▸
DERL1 ▸ ELAVL1 ▸ CEP55 ▸ NTF3 ▸ ARSA ▸ CEP89 ▸ CARD16 ▸
PTK2 ▸ IRF4 ▸ SLC17A5 ▸ CCL2 ▸ CEP170 ▸ CTNND1 ▸ CEP104 ▸
CEP68 ▸ CEP95 ▸ MIF ▸ CEP164 ▸ PSEN1 ▸ WNT1 ▸ PRKCG ▸
CEP128 ▸ IGF1R ▸ CDK4 ▸ PRKAB2 ▸ NPY6R ▸ ARC ▸ GYS1 ▸
CCR4 ▸ GPX1 ▸ PTPN11 ▸ TGM2 ▸ GLI1 ▸ CYR61 ▸ SHH ▸
PDGFB ▸ TNFRSF10B ▸ MED17 ▸ NLRC5 ▸ CPA1 ▸ ETS1 ▸ IL1RN ▸
HIPK2 ▸ PTH ▸ CDK19 ▸ IRS1 ▸ DAP3 ▸ MME ▸ SMAD7 ▸
GRP ▸ IDO1 ▸ CALML3 ▸ FAF1 ▸ CCR8 ▸ TET2 ▸ IFI44 ▸
PLD5 ▸ GNRH1 ▸ ACSM3 ▸ MED4 ▸ TFAP2A ▸ MED13 ▸ NUP62 ▸
EDNRA ▸ CD8B ▸ PLD3 ▸ SDS ▸ BNIP3 ▸ CENPK ▸ PLK1 ▸
CCK ▸ PRG2 ▸ MED24 ▸ IRF8 ▸ CDK9 ▸ NPPA ▸ SHC1 ▸
RAD18 ▸ CDK15 ▸ CCR3 ▸ VIP ▸ E2F2 ▸ NODAL ▸ PAWR ▸
DIDO1 ▸ XAF1 ▸ KMT2A ▸ FAM168B ▸ S100A12 ▸ NUP214 ▸ NANOG ▸
CSF1 ▸ NAB2 ▸ PRG3 ▸ RUNX3 ▸ MICE ▸ TAC3 ▸ CCR5 ▸
SMAD4 ▸ MED14 ▸ RAD21 ▸ COP ▸ FLT3 ▸ GYS2 ▸ RBL2 ▸
MED8 ▸ DAXX ▸ NUP43 ▸ CCR9 ▸ CDC42 ▸ PTCH1 ▸ CA8 ▸
EMP3 ▸ BLM ▸ TYR ▸ CHUK ▸ FHIT ▸ MAP2 ▸ MTX1 ▸
WNT3A ▸ QRICH1 ▸ ANXA6 ▸ SERPINA1 ▸ BAG3 ▸ NAB1 ▸ GHSR ▸
NLRP5 ▸ EIF4G3 ▸ TET1 ▸ PAN2 ▸ DAPK2 ▸ MED1 ▸ KLKB1 ▸
MT3 ▸ NUP153 ▸ TNFRSF8 ▸ GSTT1 ▸ CTRL ▸ CXCL13 ▸ GNA11 ▸
HTRA1 ▸ LGALS1 ▸ MED12 ▸ IAPP ▸ RAD1 ▸ MED21 ▸ CISH ▸
SERPINF1 ▸ ATM ▸ MAP3K7 ▸ MED6 ▸ EMP2 ▸ ANP32A ▸ THBS1 ▸
HMGCR ▸ JAK3 ▸ SERP2 ▸ EIF4G2 ▸ SATB1 ▸ DHCR24 ▸ IGFBP3 ▸
CAPNS1 ▸ ANG ▸ RAD52 ▸ CDK16 ▸ PSENEN ▸ CDK7 ▸ SEPT4 ▸
PLD6 ▸ CDK13 ▸ PPT1 ▸ CCR6 ▸ IRF9 ▸ JAK1 ▸ CDK17 ▸
CTNNBL1 ▸ ADM ▸ STX2 ▸ KLK3 ▸ SAA1 ▸ STC1 ▸ SREBF2 ▸
NTF4 ▸ GJA1 ▸ ERVK-6 ▸ SPP1 ▸ RAD50 ▸ CCL19 ▸ MTOR ▸
IFNA2 ▸ ACR ▸ MED7 ▸ TAC4 ▸ MTA2 ▸ PLD4 ▸ HDAC6 ▸
RAC3 ▸ IFNA5 ▸ MTA1 ▸ CCR1 ▸ RARA ▸ UCP2 ▸ TGFB3 ▸
FKBP4 ▸ CCR2 ▸ ACAD8 ▸ APEX1 ▸ NLRP7 ▸ PC ▸ RIPK4 ▸
NAIP ▸ SLPI ▸ NUP210 ▸ CDK20 ▸ VDAC3 ▸ AIP ▸ PIN1 ▸
BCAP31 ▸ TAC1 ▸ PGF ▸ MED26 ▸ EML2 ▸ CDK6 ▸ RAC2 ▸
KLF4 ▸ CIB1 ▸ TRAF7 ▸ QRICH2 ▸ LRP1 ▸ NR0B1 ▸ ID3 ▸
GPI ▸ ADH5 ▸ PXN ▸ CCNC ▸ CD2 ▸ MED23 ▸ SIVA1 ▸
HRK ▸ STSP1 ▸ ING1 ▸ CDK10 ▸ ODC1 ▸ SREBF1 ▸ MST1R ▸
TRA ▸ CDK3 ▸ TNFSF12 ▸ MT4 ▸ CRYAB ▸ PAN3 ▸ NANOS2 ▸
SERPINB9 ▸ SMAD3 ▸ LRRC59 ▸ NOTCH1 ▸ PARG ▸ IFIH1 ▸ NACA ▸
PAEP ▸ HTRA3 ▸ IRF7 ▸ PMEL ▸ TMED7 ▸ TSC22D3 ▸ HCLS1 ▸
ETS2 ▸ ATG3 ▸ MED15 ▸ TRAF5 ▸ CFTR ▸ MED25 ▸ E2F3 ▸
EIF4G1 ▸ HRD ▸ DLG1 ▸ CDK14 ▸ C22orf29 ▸ CDK18 ▸ RHO ▸
NUAK1 ▸ ABCD1 ▸ CDCA5 ▸ CCR10 ▸ ITCH ▸ MTA3 ▸ VDAC2 ▸
APOE ▸ APOBEC3D ▸ AFP ▸ EMP1 ▸ CFL1 ▸ ANGPT4 ▸ CDK12 ▸
CPOX ▸ PRG4 ▸ CALB1 ▸ DYRK1A ▸ APIP ▸ HDAC4 ▸ CALR ▸
TET3 ▸ ACIN1 ▸ DNAJC5 ▸ PSMB9 ▸ GPX3 ▸ HTRA4 ▸ EEF1A2 ▸
CDK1 ▸ TRAF4 ▸ NTN1 ▸ XRCC6 ▸ FUK ▸ CDK11A ▸ GAS2 ▸
SCAF11 ▸ PTGES3 ▸ TRIM28 ▸ UNC5B ▸ NUCB2 ▸ SDC2 ▸ UBC ▸
GMNN ▸ PPARGC1A ▸ RNF2 ▸ ARHGDIB ▸ EIF4A1 ▸ DBNL ▸ HNRNPU ▸
HRAS ▸ ELANE ▸ BCAR1 ▸ HNRNPD ▸ AR ▸ PPP3CA ▸ IFT57 ▸
FUS ▸ MAP4K1 ▸ TNFRSF25 ▸ NFE2L2 ▸ YWHAE ▸ NDUFS1 ▸ MEF2A ▸
PSIP1 ▸ LPAR3 ▸ CD247 ▸ MAP3K14 ▸ MDC1 ▸ GRIPAP1 ▸ YWHAG ▸
NMT2 ▸ ATG4D ▸ GORASP1 ▸ IL1R1 ▸ PICALM ▸ IQGAP1 ▸ DSG3 ▸
EIF3J ▸ EIF3S10 ▸ HEY2 ▸ SARS2 ▸ TNS4 ▸ NUMA1 ▸ NGFR ▸
PTMA ▸ UBE4B ▸ KEAP1 ▸ AIFM1 ▸ DSG1 ▸ EIF4B ▸ LPAR1 ▸
PLA2G4A ▸ CTTN ▸ SAV1 ▸ CDK11B ▸ ACTA1 ▸ ATN1 ▸ NR3C1 ▸
PLEKHO1 ▸ WNK3 ▸ PDE10A ▸ RBX1 ▸ THAP11 ▸ MAPK8IP3 ▸ PLA2G4B ▸
MAPT ▸ AKAP8 ▸ STK24 ▸ KARS ▸ PIP5K1A ▸ NFATC2 ▸ BIRC4 ▸
NVL ▸ DCTN1 ▸ FBXW11 ▸ ACVR1C ▸ DSG2 ▸ CAD ▸ RABEP1 ▸
SYF2 ▸ CDC2L1 ▸ TP73 ▸ COPS6 ▸ SOCS5 ▸ NGFRAP1 ▸ ZBTB16 ▸
PRF1 ▸ NEO1 ▸ HNRNPA0 ▸ PDE5A ▸ CDC2L2 ▸ BMX ▸ ARHGDIA ▸
IL1R2 ▸ MLH1 ▸ GZMM ▸
Data information
Please see the Gene Interactions Track Manual.