Gene interactions and pathways from curated databases and text-mining
SMC4: top 25 interacting genes (chr3:160117437-160152741)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only SMC4-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with SMC4, not among the Top 25
Other genes interacting with SMC4. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

RHOA ▸ TNF ▸ MAPK6 ▸ MAPK15 ▸ MAPK11 ▸ MAPK13 ▸ IL4 ▸
MAPK14 ▸ MAPK7 ▸ MAPK1 ▸ MAPK3 ▸ MAPK4 ▸ NOS2 ▸ MAPK12 ▸
MAPK10 ▸ MAPK9 ▸ MAPK8 ▸ MMP26 ▸ MMP25 ▸ MMP24 ▸ MMP3 ▸
JUN ▸ CCL2 ▸ MMP27 ▸ MMP1 ▸ MMP8 ▸ MMP20 ▸ PDGFRB ▸
MMP14 ▸ MMP19 ▸ MMP21 ▸ MMP12 ▸ IFNG ▸ MMP11 ▸ MMP28 ▸
IRF6 ▸ MMP7 ▸ GH1 ▸ MMP10 ▸ ROCK1 ▸ MMP13 ▸ MMP17 ▸
MMP16 ▸ IL1A ▸ MMP15 ▸ TCF15 ▸ IL6 ▸ PAPPA ▸ RETN ▸
TCF3 ▸ TCF4 ▸ GPI ▸ LPA ▸ PTPN11 ▸ FGF1 ▸ SMAD7 ▸
CHKA ▸ CA2 ▸ FOS ▸ CFP ▸ TCF19 ▸ IL3 ▸ KLF5 ▸
VEGFA ▸ TCF25 ▸ KLF4 ▸ TCF21 ▸ TCF24 ▸ PDGFRA ▸ ROCK2 ▸
BRCA1 ▸ EGR1 ▸ PDGFD ▸ MYBL2 ▸ IL10 ▸ TCF23 ▸ TCF7 ▸
S1PR2 ▸ FGFR3 ▸ TCF20 ▸ TCF12 ▸ TGFB2 ▸ TGFB3 ▸ ERBB2 ▸
SEC61A1 ▸ FLNA ▸ CANX ▸ NCL ▸ TUBB2A ▸ FAM162A ▸ YBX1 ▸
YWHAQ ▸ LGALS1 ▸ ADRM1 ▸ TAGLN2 ▸ MAGED2 ▸ IPO13 ▸ DKC1 ▸
HJURP ▸ DHRS7 ▸ MBD3 ▸ RPL31 ▸ POLR2A ▸ SRRM2 ▸ SCO2 ▸
ACOT8 ▸ RPN2 ▸ BCR ▸ ATP1B3 ▸ RPLP2 ▸ RPSA ▸ PMPCA ▸
TF ▸ LIG4 ▸ PRPF6 ▸ HIST1H3I ▸ SNRNP200 ▸ ATP5J ▸ PLK1 ▸
AKAP8L ▸ CDK19 ▸ KDM1A ▸ GTF3C6 ▸ FANCI ▸ RANGAP1 ▸ SLC37A4 ▸
SMC1A ▸ TFRC ▸ PHIP ▸ MRPS34 ▸ DNTTIP2 ▸ RPS27L ▸ NDUFA8 ▸
MED9 ▸ PLEC ▸ UBE2S ▸ LMAN2 ▸ AFAP1 ▸ HYOU1 ▸ RAB5C ▸
CSE1L ▸ FOXK2 ▸ HSD17B12 ▸ NUP85 ▸ NUP93 ▸ DDX52 ▸ POLR3H ▸
PCBP2 ▸ HHIP ▸ SNW1 ▸ TFIP11 ▸ TUBG1 ▸ PNN ▸ POLR2F ▸
TRAFD1 ▸ PCBP1 ▸ KPNA2 ▸ CKAP4 ▸ STAT1 ▸ DNMT3B ▸ MAGED1 ▸
IKBKG ▸ POLR1D ▸ TRAP1 ▸ NEK9 ▸ PTRF ▸ NEDD8 ▸ PRKDC ▸
GEMIN4 ▸ RPL9 ▸ GCFC2 ▸ CDK2 ▸ IPO4 ▸ CDK9 ▸ RAB10 ▸
DDX20 ▸ RBM12B-AS1 ▸ ERBB2IP ▸ MED27 ▸ SMC3 ▸ COPG1 ▸ SDF2L1 ▸
CAMK2D ▸ PPAN ▸ MED29 ▸ UTP18 ▸ MCC ▸ SLC25A13 ▸ XRCC6 ▸
YWHAZ ▸ DNM2 ▸ FOXP1 ▸ EFTUD2 ▸ PPP6R3 ▸ CDK1 ▸ PCYOX1 ▸
ACTB ▸ LMNA ▸ NDUFA10 ▸ KDELR2 ▸ CCDC85C ▸ MYBBP1A ▸ ALG1 ▸
PSMC2 ▸ RFT1 ▸ CDK8 ▸ HDAC2 ▸ FBL ▸ HIST1H3J ▸ GATAD2A ▸
ATP5H ▸ ATP2A2 ▸ CCT5 ▸ H1FX ▸ NCAPD2 ▸ HNRNPF ▸ IKBKE ▸
BAX ▸ HSPA1L ▸ IPO9 ▸ LEPRE1 ▸ LYPLAL1 ▸ PCNA ▸ HIST1H3B ▸
LZTR1 ▸ HIST1H3G ▸ MLLT11 ▸ SNRPF ▸ CPT2 ▸ EIF2S1 ▸ PHB ▸
SSSCA1 ▸ STOML2 ▸ ALDH1B1 ▸ VAT1 ▸ MDH2 ▸ HNRNPA0 ▸ COPB1 ▸
NOL8 ▸ SLC25A22 ▸ SMARCA5 ▸ RPL27 ▸ CCAR2 ▸ ETV3 ▸ SLC39A7 ▸
POLR1E ▸ MED6 ▸ AHSA1 ▸ HDAC11 ▸ ERLIN2 ▸ LETM1 ▸ RPL6 ▸
LMNB2 ▸ YBX2 ▸ NOP56 ▸ TP53 ▸ MED17 ▸ RB1 ▸ RPS7 ▸
ZBTB9 ▸ PPIG ▸ MRPS22 ▸ GTF3C1 ▸ RBM28 ▸ MRPL53 ▸ TOMM70A ▸
XRN1 ▸ CHD4 ▸ PSME4 ▸ MED13L ▸ CCT6A ▸ ZCCHC10 ▸ WDR74 ▸
PPP2CB ▸ STT3A ▸ LONP1 ▸ UBC ▸ GSG2 ▸ CLN6 ▸ TBC1D4 ▸
SEC16A ▸ DDX5 ▸ ZMPSTE24 ▸ RBM39 ▸ CYB5B ▸ VDAC2 ▸ PTGES2 ▸
TARS2 ▸ XRCC1 ▸ CPT1A ▸ GLUD1 ▸ NOC4L ▸ UBD ▸ PTPN14 ▸
SRR ▸ PDLIM7 ▸ IGF2BP2 ▸ SRPRB ▸ TMPO ▸ RPLP0 ▸ SERBP1 ▸
MED18 ▸ MED15 ▸ RPS27 ▸ POLR2B ▸ POLR2L ▸ RNGTT ▸ CCT2 ▸
IKBKAP ▸ C1QBP ▸ MED1 ▸ ATAD2 ▸ POLR3A ▸ RPL13 ▸ MED25 ▸
PPP1CA ▸ ABHD12 ▸ TM9SF2 ▸ ATG2B ▸ RPL35 ▸ ATP5A1 ▸ FHL2 ▸
CYB5R3 ▸ HEATR1 ▸ ERP44 ▸ POLR2D ▸ PSMC4 ▸ SLC25A19 ▸ UFL1 ▸
PPT1 ▸ NOP58 ▸ SF3B2 ▸ MED8 ▸ TOP2A ▸ NDUFAF4 ▸ RHBDD2 ▸
HSPBP1 ▸ DNAJB12 ▸ ATP5L ▸ IPO7 ▸ LMAN1 ▸ MED7 ▸ RPL36 ▸
BAG2 ▸ SFXN1 ▸ RANBP1 ▸ ANAPC5 ▸ U2SURP ▸ GNB3 ▸ ARF1 ▸
C19orf70 ▸ THRAP3 ▸ AUP1 ▸ ADNP ▸ ILVBL ▸ MYO9A ▸ PHGDH ▸
PMPCB ▸ SDHA ▸ SLC25A21 ▸ TTC27 ▸ NABP2 ▸ TECR ▸ GCDH ▸
RPL17 ▸ SDF4 ▸ SF3B6 ▸ UBE2C ▸ COX5A ▸ MED24 ▸ TFAM ▸
COG6 ▸ PSMA3 ▸ SHOC2 ▸ PHLDA3 ▸ COPB2 ▸ SYNGR1 ▸ DNAJC11 ▸
CCT3 ▸ DDOST ▸ MED10 ▸ XAB2 ▸ RNF130 ▸ RAD23A ▸ CALM1 ▸
TCOF1 ▸ KPNA4 ▸ LAGE3 ▸ FAF2 ▸ PSMC3 ▸ HIST1H2BL ▸ RPL3 ▸
PPP2R1A ▸ EEF1G ▸ HIST1H4A ▸ RFC5 ▸ SMYD2 ▸ AP1G1 ▸ SLC25A3 ▸
PSMD4 ▸ MED16 ▸ PSMA5 ▸ FANCD2 ▸ RUVBL2 ▸ TRRAP ▸ IDH3B ▸
STIP1 ▸ XPOT ▸ C3 ▸ HSPA4L ▸ POLE ▸ DDX3X ▸ PSMC6 ▸
ADIPOR1 ▸ TENC1 ▸ MTA2 ▸ RPL5 ▸ SLC16A1 ▸ XPO1 ▸ MAD2L1 ▸
TOP1 ▸ HADHA ▸ NDUFS2 ▸ HIST1H3C ▸ PSMB1 ▸ SSBP1 ▸ YY1 ▸
IGF2BP1 ▸ KRTCAP2 ▸ HSPA9 ▸ MLF2 ▸ NOP2 ▸ OAT ▸ TUBB2B ▸
CDC23 ▸ GTF2I ▸ PTPLAD1 ▸ RUNX1 ▸ ELL2 ▸ PTBP1 ▸ DNAJC7 ▸
ARL8A ▸ ETFA ▸ ZNF326 ▸ CHCHD6 ▸ GTF3C2 ▸ ATP2A3 ▸ CHP1 ▸
KPNA6 ▸ VDAC1 ▸ TUBB3 ▸ FAR1 ▸ BZW1 ▸ PNKD ▸ TKT ▸
IMMT ▸ ZNF121 ▸ EPHX1 ▸ MDN1 ▸ GANAB ▸ RAF1 ▸ POLR2I ▸
CHTF18 ▸ CLPB ▸ IRS4 ▸ FOXK1 ▸ ERCC3 ▸ ALDH18A1 ▸ OSGEP ▸
ACACA ▸ BCLAF1 ▸ COPA ▸ DNAJA3 ▸ OPA1 ▸ WDR33 ▸ MED14 ▸
DNAJA4 ▸ RBM22 ▸ GID8 ▸ AURKB ▸ FN1 ▸ GTF3C5 ▸ PRKCDBP ▸
ANAPC2 ▸ RFC4 ▸ EXOSC2 ▸ EEF2 ▸ RNF219 ▸ RPL21 ▸ SKP1 ▸
PRPF4B ▸ YBX3 ▸ ESYT2 ▸ RPL23 ▸ CIRH1A ▸ SLIT2 ▸ PSMD2 ▸
DNALI1 ▸ MTA1 ▸ XRCC5 ▸ BCAP31 ▸ HNRNPDL ▸ POLDIP2 ▸ SSR1 ▸
MYC ▸ RPS4X ▸ SLC25A1 ▸ MED26 ▸ SLC25A11 ▸ TUBB6 ▸ SQRDL ▸
STAG1 ▸ ANXA2 ▸ HNRNPD ▸ TMEM33 ▸ IGF2BP3 ▸ TUBA1C ▸ TIMM10 ▸
SEC61B ▸ SRP9 ▸ HELLS ▸ NCAPG ▸ CLTA ▸ EBNA1BP2 ▸ HSPD1 ▸
IKZF1 ▸ EEF1A1 ▸ YLPM1 ▸ CCDC124 ▸ SLC25A5 ▸ RBBP4 ▸ SMN1 ▸
TTN ▸ AASS ▸ RPL18 ▸ PPP2R1B ▸ CLPX ▸ IMPDH2 ▸ RAD21 ▸
RPL24 ▸ RPL7 ▸ ATP5F1 ▸ S100A11 ▸ DDB1 ▸ AP3S1 ▸ VAPA ▸
POLR2G ▸ DDX21 ▸ RPL23A ▸ ARHGEF2 ▸ PSMA1 ▸ FBXW7 ▸ ABCB7 ▸
MZT2B ▸ MAT2A ▸ C2orf47 ▸ DARS ▸ FKBP8 ▸ SERPINH1 ▸ ACTC1 ▸
AFF4 ▸ CBWD6 ▸ RCN1 ▸ COX6C ▸ TMED2 ▸ CLPP ▸ RPL8 ▸
EEF1B2 ▸ EIF3I ▸ NCAPH2 ▸ PABPC1 ▸ SLC3A2 ▸ CMSS1 ▸ DNAJB1 ▸
RBPJ ▸ NCAPH ▸ PPP2R5C ▸ TTC1 ▸ GCN1L1 ▸ TIMM23 ▸ SIRT7 ▸
HM13 ▸ SLC1A5 ▸ MED12 ▸ PSMD6 ▸ RPL26 ▸ ZNF281 ▸ GFPT2 ▸
TCEB1 ▸ PGD ▸ RPL29 ▸ PGRMC1 ▸ NETO1 ▸ KIF4A ▸ SPTLC1 ▸
CEBPZ ▸ KPNB1 ▸ M6PR ▸ PAXBP1 ▸ RARS ▸ TCP1 ▸ VAMP3 ▸
TMED10 ▸ PPP6C ▸ DNAJA1 ▸ POLR2H ▸ LAMP1 ▸ PSMC1 ▸ SSR4 ▸
TMEM205 ▸ RAB14 ▸ RPN1 ▸ WDR36 ▸ CAD ▸ MYCBP2 ▸ ASS1 ▸
AHCTF1 ▸ POLR3F ▸ TTF2 ▸ POLR1B ▸ HADHB ▸ SSR3 ▸ YWHAB ▸
DDX1 ▸ HIST1H3A ▸ DHX15 ▸ COX17 ▸ NUP153 ▸ RBMS2 ▸ LMNB1 ▸
UBTF ▸ RANBP9 ▸ COX4I1 ▸ RAB11A ▸ SMTN ▸ AIFM1 ▸ DIMT1 ▸
MED21 ▸ IDH3A ▸ WDR6 ▸ ATXN2L ▸ HIST1H3D ▸ SLC7A5 ▸ NUP98 ▸
MOGS ▸ POLR2E ▸ NDUFA5 ▸ AKAP8 ▸ RCN2 ▸ RPS3A ▸ SARS ▸
RAB1B ▸ WDR77 ▸ HIGD1A ▸ CALU ▸ MARS ▸ RIF1 ▸ AFG3L2 ▸
NUP205 ▸ NDUFAF3 ▸ RANBP2 ▸ RPL4 ▸ CDIPT ▸ UQCRC2 ▸ ACTL6A ▸
RPAP2 ▸ NOLC1 ▸ DDX31 ▸ TRIM21 ▸ ACTG1 ▸ NAP1L1 ▸ RPS28 ▸
POLR2J ▸ DHRS7B ▸ QPCTL ▸ IFIH1 ▸ LRPPRC ▸ RPL15 ▸ NDUFS7 ▸
THOC2 ▸ WRNIP1 ▸ SF3A1 ▸ PARP1 ▸ ZFR ▸ PHB2 ▸ PPP6R1 ▸
SLC25A4 ▸ ATP6V1E1 ▸ HIST1H3E ▸ ACIN1 ▸ ATP5D ▸ EMD ▸ CTNND1 ▸
GEMIN2 ▸ SET ▸ TNPO2 ▸ U2AF1 ▸ MAPKAP1 ▸ TUBB ▸ TIMM13 ▸
PDCD11 ▸ EIF3B ▸ FAM186B ▸ ERC1 ▸ CDYL ▸ MED4 ▸ TXN ▸
RSL1D1 ▸ NIPSNAP1 ▸ TSN ▸ SLC25A33 ▸ PLOD3 ▸ FOSL1 ▸ GTF3C4 ▸
RFC3 ▸ SUCLG1 ▸ TUBGCP2 ▸ ECSIT ▸ TCEB2 ▸ BDH1 ▸ DNAJB2 ▸
PSMA7 ▸ CSNK2B ▸ MED22 ▸ RPS14 ▸ EIF3E ▸ HSP90AA1 ▸ ALYREF ▸
HSP90AB1 ▸ AGPS ▸ RPLP1 ▸ SUGT1 ▸ CYC1 ▸ CYR61 ▸ PML ▸
DPM1 ▸ CCDC47 ▸ RAB21 ▸ SF3B3 ▸ UTP6 ▸ MCPH1 ▸ ATP5O ▸
ATP1A1 ▸ KIAA0368 ▸ NDUFS1 ▸ NUP133 ▸ RUVBL1 ▸ HDAC1 ▸ ANAPC1 ▸
ARL1 ▸ PGRMC2 ▸ DIS3 ▸ RAB6A ▸ UBE3C ▸ EPRS ▸ NDUFA13 ▸
IARS ▸ RPL12 ▸ TUBA1A ▸ EP400 ▸ EIF4ENIF1 ▸ UQCRC1 ▸ MSH3 ▸
SIN3A ▸ CEPT1 ▸ MCCC2 ▸ TUBB4A ▸ HCFC1 ▸ NUMA1 ▸ ZMYM2 ▸
CBFB ▸ CCT8 ▸ DDX50 ▸ CDC42EP1 ▸ RNH1 ▸ SACM1L ▸ MED31 ▸
UTP14A ▸ SMC2 ▸ PC ▸ YWHAE ▸ PSMB3 ▸ ARF4 ▸ PELO ▸
TUBA1B ▸ ATP5C1 ▸ ATP5J2 ▸ SON ▸ TUBB4B ▸ SV2A ▸ PTRH2 ▸
RPL19 ▸ ASPH ▸ SQSTM1 ▸ AGK ▸ MYO5C ▸ PPP2R5E ▸ MYO9B ▸
CHCHD3 ▸ PPP2CA ▸ STAT2 ▸ TRAF3IP1 ▸ TRIM28 ▸ PES1 ▸ TUBA4A ▸
BAZ1B ▸ MGME1 ▸ MED23 ▸ SCAMP3 ▸ TMEM109 ▸ MED13 ▸ SMARCC1 ▸
TMX1 ▸ DYNC1H1 ▸ XPO5 ▸ RRP12 ▸ SRSF2 ▸ ST13 ▸ NCAPD3 ▸
SYNJ2BP ▸ SLC25A42 ▸ MT-CO2 ▸ SUMO2 ▸ SLC25A10 ▸ HDAC6 ▸ PSMA4 ▸
DNAJB11 ▸ CHD9 ▸ TIMM50 ▸ COPG2 ▸ DDX39B ▸ POLD1 ▸ RNPS1 ▸
TRMT1L ▸ DNAJB6 ▸ USMG5 ▸ IK ▸ SLC25A6 ▸ VCP ▸ CFL1 ▸
RPS6 ▸ CSNK2A2 ▸ SLC25A12 ▸ IDH3G ▸ SMN2 ▸ MED11 ▸ CCT4 ▸
SNRPD1 ▸ DNAJA2 ▸ PSMC5 ▸ HNRNPM ▸ CASP4 ▸ HSPA6 ▸ MED20 ▸
IQGAP2 ▸ CTPS1 ▸ SLC2A1 ▸ DDX27 ▸ LUC7L3 ▸ RFC2 ▸ SLC25A18 ▸
HNRNPH1 ▸ PSMA2 ▸ PSMB5 ▸ CCNC ▸ ARCN1 ▸ TARDBP ▸ NDUFA4 ▸
IQGAP3 ▸ SUMO1 ▸ SYNE2 ▸ HIST1H3F ▸ RPP30 ▸ TNPO3 ▸ POLR1A ▸
RBM14 ▸ DDX17 ▸ ETV5 ▸ RAB7A ▸ TIMMDC1 ▸ HSPB1 ▸ MAX ▸
DAD1 ▸ GIGYF1 ▸ PI4KA ▸ PSMB4 ▸ ATXN10 ▸ NOMO3 ▸ POLR2C ▸
OSBPL8 ▸ HUWE1 ▸ EIF2S3 ▸ RPL22 ▸ DHCR7 ▸ GTF3C3 ▸ SRSF3 ▸
RCOR2 ▸ USP7 ▸ RBM34 ▸ CCT7 ▸ LARS ▸ PHLDB2 ▸ SH3BP4 ▸
DICER1 ▸ HNRNPK ▸ MCM7 ▸ NPM1 ▸ POLR3B ▸ MED19 ▸ RABL6 ▸
SEC22B ▸ EIF3H ▸ EIF4A1 ▸ MSH6 ▸ NCAPG2 ▸ PRPF8 ▸ MTHFD2 ▸
STUB1 ▸ MED30 ▸ IRAK1 ▸ RBBP7 ▸ FBXW8 ▸ HIST1H3H ▸ NDUFS3 ▸
STAT3 ▸ HAX1 ▸ DDX6 ▸ P4HA1 ▸ TOMM22 ▸ HSPA4 ▸ HSPA1A ▸
PSMD3 ▸ NONO ▸ MMS19 ▸ HSPH1 ▸
Data information
Please see the Gene Interactions Track Manual.