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ETS1 — MYLIP
Text-mined interactions from Literome
Itoh et al., J Biol Chem 2010
:
In the present study, using microRNA array and in silico analyses, we found that
miR-208 is closely
involved in preosteoblast differentiation by partially regulating the expression of
Ets1 ( V-ets erythroblastosis virus E26 oncogene homolog 1 ), which transactivates osteopontin, runt related transcription factor 2, parathyroid hormone related protein, and type I procollagen
Mattia et al., Pigment Cell Melanoma Res 2011
:
Differently from 293FT cells or early stage melanomas, where unphosphorylated
ETS-1 represses
miR-222 transcription, in metastatic melanoma the constitutively Thr-38 phosphorylated fraction of ETS-1 induces miR-222
Roy et al., Microcirculation 2012
(Anoxia...) :
We further demonstrated that hypoxia-sensitive
miR-200b is
involved in induction of angiogenesis by directly targeting
Ets-1 in HMECs
Zheng et al., Mol Cancer Res 2013
(Neoplasm Invasiveness...) :
In addition, the
effects of
miR-145 on
Ets1 expression, migration, invasion, and angiogenesis were rescued by restoration of Ets1 expression in these cells
Zheng et al., PloS one 2013
(Neoplasm Invasiveness...) :
Ectopic expression or knockdown of
miR-9 resulted in responsively altered expression of cyclin D1,
Ets1 and their downstream targets phosphorylated retinoblastoma and matrix metalloproteinase 9 in cultured gastric cancer cell lines SGC-7901 and AGS ... Restoration of
miR-9 mediated down-regulation of cyclin D1 and
Ets1 by transient transfection, rescued the cancer cells from decrease in proliferation, migration and invasion