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MYLIP — WNT11
Text-mined interactions from Literome
Kapinas et al., J Cell Biochem 2009
:
These data suggest that canonical
Wnt signaling, which is increased during osteoblastic differentiation,
induces expression of
miR-29
Kapinas et al., J Biol Chem 2010
:
Specifically, canonical
Wnt signaling
induces miR-29a transcription
Zhang et al., J Bone Miner Res 2011
:
In conclusion,
miR-335-5p activates
Wnt signaling and promotes osteogenic differentiation by downregulating DKK1
Zhou et al., Oncogene 2012
(Neoplasm Invasiveness...) :
Mechanistically, three TCF/LEF1 binding elements (TBEs) were identified in the promoter region and shown to be required for
Wnt dependent activation of
miR-371-373
Strillacci et al., J Pathol 2013
(Adenocarcinoma...) :
Loss of
miR-101 expression
promotes Wnt/ß-catenin signalling pathway activation and malignancy in colon cancer cells
Hassan et al., J Biol Chem 2012
(Mammary Neoplasms, Animal...) :
In turn,
miR-218 expression is up-regulated in
response to stimulated
Wnt signaling and functionally drives Wnt related transcription and osteoblast differentiation, thereby creating a positive feedback loop ... Furthermore, in metastatic breast cancer cells but not in normal mammary epithelial cells,
miR-218 enhances
Wnt activity and abnormal expression of osteoblastic genes ( osteomimicry ) that contribute to homing and growth of cells metastatic to bone
Hu et al., Mol Med Report 2013
:
The adenomatous polyposis coli (APC) gene was a direct target of miR-142-3p, whereby
miR-142-3p promoted
Wnt signaling through inhibition of APC, leading to accumulation and nuclear translocation of ß-catenin
Zhang et al., J Clin Endocrinol Metab 2013
(Carcinoma...) :
We have searched for miR-155 targets and identified the hypothesis that
miR-155 could promote tumor growth of PTC by targeted regulation of adenomatous polyposis coli (APC) expression and
activating the
Wnt/ß-catenin signaling ... By targeting APC,
miR-155 efficiently
regulates the
Wnt/ß-catenin signaling