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INS — TGM5
Text-mined interactions from Literome
Lindsay et al., Biosci Rep 1990
:
Ca ( 2+ ) -Induced
insulin release from electropermeabilised islets is
inhibited by the
transglutaminase inhibitors monodansylcadaverine, glycine methylester, methylamine and cystamine but not by the control compounds dimethyl monodansylcadaverine and sarcosine methylester which lack the primary amine group
Sener et al., Endocrinology 1985
:
Role of
transglutaminase in
insulin release
Bungay et al., Biochem J 1986
:
A
role for
transglutaminase in glucose stimulated
insulin release from the pancreatic beta-cell
Nowak et al., Metabolism 1983
:
Extrapancreatic action of sulfonylureas : hypoglycemic effects are not dependent on altered
insulin binding or
inhibition of
transglutaminase ... Thus, the hypoglycemia caused by sulfonylurea administration could not be attributed to increases in insulin binding,
inhibition of
transglutaminase activity, or enhanced
insulin levels
Driscoll et al., Pancreas 1997
(Insulinoma...) :
To examine whether
transglutaminase could
mediate effects of retinoids on
insulin secretion, we measured ( i ) transglutaminase activity in islets from rats deficient in vitamin A or repleted with retinol or retinoic acid, ( ii ) transglutaminase activity in RINm5F and INS-1 insulin secreting cells cultured in retinol or retinoic acid, ( iii ) mRNA for transglutaminase in RINm5F and INS-1 cells, and ( iv ) insulin secretion from INS-1 cells in response to retinoic acid