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DAP — TLR2

Text-mined interactions from Literome

Chu et al., Eur J Immunol 2008 : In this report, we demonstrate that both DAP12 and the FcepsilonRIgamma-chain (FcRgamma) are required for negative regulation of TLR responses in bone marrow derived dendritic cells ( DC )
Peng et al., Science signaling 2013 : DAP12 inhibits Toll-like receptor ( TLR ) signaling, such as that of TLR4 in response to its ligand lipopolysaccharide (LPS), as well as cytokine responses by coupling to TREM2 ( triggering receptor expressed on myeloid cells 2 ) at the plasma membrane