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BPNT1 — IL4
Text-mined interactions from Literome
Leonardi et al., Invest Ophthalmol Vis Sci 2003
(Conjunctivitis, Allergic) :
IL-4 and -13 ( 10 ng/mL ) significantly
increased production and expression of
PIP compared with nonstimulated cells, whereas IFN-gamma elicited the opposite effect, at both the protein and mRNA levels
Hirve et al., PloS one 2012
:
We found that FYF triple mutation
inhibits the TCR induced production of
IL-4 by impairing ITK binding to
PIP ( 3 ), reducing ITK membrane recruitment, inducing conformational changes at the T cell-APC contact site, and compromising phosphorylation of ITK and subsequent phosphorylation of PLC? ( 1 )