Gene interactions and pathways from curated databases and text-mining

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CASP1 — NLRC5

Text-mined interactions from Literome

Wu et al., J Clin Immunol 2010 (Listeriosis) : Here, we have used macrophages from AIM2-, NLRC4-, NLRP3-, and ASC-deficient mice to demonstrate that AIM2, NLRC4 , and NLRP3 inflammasomes as well as the adaptor protein ASC all contribute to activation of caspase-1 in Listeria infected macrophages
Staehli et al., J Immunol 2012 : NLRC5 was sufficient to induce MHC I expression in a human lymphoid cell line, requiring both caspase recruitment and LRR domains