Gene interactions and pathways from curated databases and text-mining

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CASP1 — SP1

Text-mined interactions from Literome

Su et al., Biochem J 2000 : Human Sug1/p45 is involved in the proteasome dependent degradation of Sp1
Miyoshi et al., Biochem Biophys Res Commun 2005 : Experiments using a GC-specific DNA binding agent, mithramycin A, and an electrophoretic mobility shift assay demonstrated that Sp1 might mediate the enhanced expression of caspase-3
Sudhakar et al., FEBS J 2008 : The caspase-3 promoter was activated by Sp1 in Sp1-deficient Drosophila SL-2 cells
Meng et al., PLoS Pathog 2012 : We further show that cleavage of preassembled CA-SP1-NC by HIV-1 protease in vitro leads to release of SP1 and NC without disassembly of the lattice
Kikuchi et al., J Biol Chem 2013 (Multiple Myeloma) : K-7174 induces transcriptional repression of class I histone deacetylases ( HDAC1, -2, and -3 ) via caspase-8 dependent degradation of Sp1 , the most potent transactivator of class I HDAC genes