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CASP1 — TXN
Text-mined interactions from Literome
Andoh et al., J Biol Chem 2003
:
The activated PKG is required to protect cells from lipid peroxidation and apoptosis, to
inhibit caspase-9 and caspase-3 activation, and to elevate the levels of Trx peroxidase-1 and
Trx , which subsequently induces the expression of Bcl-2
Ramachandiran et al., Toxicological sciences : an official journal of the Society of Toxicology 2007
(Parkinsonian Disorders) :
Divergent mechanisms of paraquat, MPP+, and rotenone toxicity : oxidation of
thioredoxin and
caspase-3 activation
Wang et al., Ann Neurol 2007
(Hypoxia-Ischemia, Brain) :
Protection by NAC was associated with the following factors : ( 1 ) reduced isoprostane activation and nitrotyrosine formation ; ( 2 ) increased levels of the antioxidants glutathione,
thioredoxin-2 , and ( 3 ) inhibition of caspase-3, calpain, and
caspase-1 activation
Arai et al., Toxicol Appl Pharmacol 2008
:
A role for TRX-1 expression on GSNO catabolism and cell viability was demonstrated by the concentration dependent effects of GSNO on decreasing
TRX-1 expression,
activation of
caspase-3 , and increasing cell death ... The over-expression of
TRX-1 in HeLa cells partially
attenuated caspase-3 activation and enhanced cell viability upon GSNO treatment
Ueda et al., J Immunol 1998
(Necrosis) :
Redox regulation of
caspase-3 ( -like ) protease activity : regulatory
roles of
thioredoxin and cytochrome c