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FGF10 — PIK3CA

Pathways - manually collected, often from reviews:

• Reactome Reaction: FGF10 → PIK3CA (indirect_complex) Ong et al., Proc Natl Acad Sci U S A 2001, Guasch et al., Mol Cell Biol 2001, Demiroglu et al., Blood 2001, Agazie et al., Oncogene 2003, Chen et al., Proc Natl Acad Sci U S A 2004, Eswarakumar et al., Cytokine Growth Factor Rev 2005, Takeda et al., Clin Cancer Res 2007, Byron et al., Cancer Res 2008, Wesche et al., Biochem J 2011
• Reactome Reaction: FGF10 → PIK3CA (reaction) Ong et al., Proc Natl Acad Sci U S A 2001, Guasch et al., Mol Cell Biol 2001, Demiroglu et al., Blood 2001, Agazie et al., Oncogene 2003, Chen et al., Proc Natl Acad Sci U S A 2004, Eswarakumar et al., Cytokine Growth Factor Rev 2005, Takeda et al., Clin Cancer Res 2007, Byron et al., Cancer Res 2008, Wesche et al., Biochem J 2011

Text-mined interactions from Literome

Koyama et al., Dev Growth Differ 2008 : However, FGF7 and FGF10 stimulated phosphorylation of both PLCgamma1 and PI3K , but elicited only minimal phosphorylation of ERK-1/2
Lawson et al., Proc Natl Acad Sci U S A 2010 (Disease Models, Animal...) : Stromal induction of FGF signaling, increased expression of the ETS family transcription factor ERG1, and constitutive activation of PI3K signaling were evaluated
Dey et al., Cancer Res 2010 (Lung Neoplasms...) : Targeting fibroblast growth factor receptors blocks PI3K/AKT signaling, induces apoptosis, and impairs mammary tumor outgrowth and metastasis