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CCR5 — IL13

Text-mined interactions from Literome

Bailer et al., Eur J Immunol 2000 : In the presence of IL-13 and TNF-alpha, expression of CCR5 was completely abrogated while the expression of CD4 and CXCR4 remained significantly reduced as compared to untreated controls
Biasin et al., J Infect Dis 2000 : However, interleukin (IL)-6 , IL-10, IL-12, interferon (IFN)-gamma, and tumor necrosis factor (TNF)-alpha and -beta mRNA were elevated in PBMC and cervical mucosa biopsy specimens of ESN and HIV infected women ; CCR5 and CXCR4 mRNA were augmented in cervical mucosa biopsy specimens, but not in PBMC, of ESN and HIV infected women ; HIV-specific IFN-gamma secreting cells were detected in vaginal washes of ESN and HIV infected women ; and phenotypic alterations were present in PBMC of ESN women
Zhang et al., Arthritis Rheum 2005 (Arthritis, Rheumatoid) : In contrast, interleukin-12 stimulation induced the up-regulation of CCR5 and a shift in the in vivo homing pattern away from the lymph nodes toward the inflamed synovium
Ma et al., J Immunol 2006 (Inflammation) : To test this hypothesis, we evaluated the effects of IL-13 on the expression of CCR5 in the murine lung
Creery et al., Viral Immunol 2006 : Differential regulation of CXCR4 and CCR5 expression by interleukin (IL)-4 and IL-13 is associated with inhibition of chemotaxis and human immunodeficiency Virus ( HIV ) type 1 replication but not HIV entry into human monocytes ... In this study, we investigated the effects of IL-4 and IL-13 on the expression of CXCR4 and CCR5 , and the biological implications of alteration of CXCR4 and CCR5 regulation on monocytic cells with respect to their migration in response to chemokines, HIV entry, and its replication ... Although IL-13 inhibited the expression of both CXCR4 and CCR5 , this downregulation of chemokine receptor expression was not sufficient to prevent virus entry
Catley et al., IDrugs 2010 (Asthma...) : This conference report highlights selected presentations on mAb treatments for asthma, including targeting IL-5, IL-13 , IL-9 and TNFa, CCR3 inhibitors , histamine H4 receptor inhibition, novel mouse models of COPD and inhaled antisense asthma therapies
Wang et al., Thorax 2013 (Asthma...) : However, CCR8 inhibition had no significant effect on allergen induced BAL eosinophilia and the induction of the Th2 cytokines IL-4, IL-5, IL-13 and mucus levels in BAL
Wang et al., J Virol 1998 : IL-4 or IL-13 also prevented the stimulatory effects of M-CSF or GM-CSF on CCR5 expression as well as HIV-1 entry and replication