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ADORA1 — MAPK7

Text-mined interactions from Literome

Robinson et al., Eur J Pharmacol 2001 : Regulation of p42/p44 MAPK and p38 MAPK by the adenosine A(1) receptor in DDT ( 1 ) MF-2 cells ... Furthermore, adenosine A(1) receptor mediated increases in p42/p44 MAPK were sensitive to the MAPK kinase 1 inhibitor PD 98059 ( 2'-amino-3'-methoxyflavone ), whereas p38 MAPK responses were blocked by the p38 MAPK inhibitor SB 203580 ( 4- ( 4-fluorophenyl ) -2- ( 4-methylsulfinylphenyl ) -5- ( 4-pyridyl ) 1H-imidazole ) ... Furthermore, adenosine A(1) receptor mediated increases in p42/p44 MAPK were sensitive to the MAPK kinase 1 inhibitor PD 98059 ( 2'-amino-3'-methoxyflavone ), whereas p38 MAPK responses were blocked by the p38 MAPK inhibitor SB 203580 ( 4- ( 4-fluorophenyl ) -2- ( 4-methylsulfinylphenyl ) -5- ( 4-pyridyl ) 1H-imidazole ) ... Furthermore, the protein kinase C inhibitors Ro 31-8220 ( 3- [ 1- [ 3- ( 2-isothioureido ) propyl ] indol-3-yl ] -4- ( 1-methylindol-3-yl ) -3-pyrrolin-2,5-dione ), chelerythrine and GF 109203X ( 2- [ 1- ( 3-dimethylaminopropyl ) -1H-indol-3-yl ] -3- ( 1H-indol-3-yl ) -maleimide ) were without effect on adenosine A(1) receptor induced p42/p44 MAPK phosphorylation ... Finally, adenosine A(1) receptor stimulation in DDT ( 1 ) MF-2 cells also activated p38 MAPK but not JNK via a pertussis toxin-sensitive pathway ... Finally, adenosine A(1) receptor stimulation in DDT ( 1 ) MF-2 cells also activated p38 MAPK but not JNK via a pertussis toxin-sensitive pathway
Lasley et al., Am J Physiol Heart Circ Physiol 2005 (Myocardial Infarction) : Delayed adenosine A1 receptor preconditioning in rat myocardium is MAPK dependent but iNOS independent
Ballard-Croft et al., Am J Physiol Heart Circ Physiol 2008 (MAP Kinase Signaling System) : However, the adenosine A(1) receptor mediated MAPK activation does not involve ROS formation