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CXCL10 — MAPK7

Text-mined interactions from Literome

Pisegna et al., Blood 2004 : Finally, we demonstrate that p38 MAPK activity is required for the dsRNA dependent enhancement of cytotoxicity and CXCL10 production
Si et al., J Immunol 2004 (Acquired Immunodeficiency Syndrome) : Adenoviral transduction of super-repressor IkappaBalpha, dominant negative MKK6, and dominant negative Ras demonstrated that NF-kappaB and p38 MAPK were involved in LPS induced IFN-inducible protein 10/CXCL10 production
Ottonello et al., Cell Signal 2005 : When the activation of ERK-1/2 and p38 MAPK by CCL3 and the classical neutrophilic chemokine CXCL8 ( IL-8 ) were compared, both the chemokines were capable of activating p38 MAPK
Méndez-Samperio et al., Cell Immunol 2005 (MAP Kinase Signaling System) : Our data also demonstrate that M. bovis BCG induced CXC chemokine ligand ( CXCL ) 8 release in epithelial cells was reduced by a mitogen activated protein/ERK kinase ( MEK ) inhibitor ( PD98059 ), but not by a p38 MAPK ( SB203580 ) inhibitor
Nakamichi et al., J Neurochem 2005 : Taken together, these results suggest that the recognition of dsRNA structure selectively induces the CXCL10 and CCL5 responses in microglia through vacuolar pH-dependent activation of NF-kappaB and MAPK signaling pathways
Wong et al., Allergy 2006 : Using various selective inhibitors for signaling molecules, we found that the inductions of IL-8, MCP-1, and I-309 were mediated by either SCF activated ERK or TNF-alpha activated p38 MAPK, while the induction of IP-10 by TNF-alpha was mediated by both activated p38 MAPK and NF-kappaB
Lane et al., Int Immunol 2006 : However, wild-type Cbl or its mutants had no effect on the CXCL8 induced activation of MAPK , indicating that Cbl specifically modulated CXCL8 induced chemotaxis
Kanda et al., Endocrinology 2007 (MAP Kinase Signaling System...) : Inhibitors of Janus kinase ( JAK ), p38 MAPK , and MAPK/ERK kinase (MEK) suppressed prolactin- plus IFN-gamma induced CXCL9, CXCL10 , and CXCL11 production and NF-kappaB, STAT1, and IRF-1 activities
Kanda et al., Eur J Immunol 2007 : Inhibitors of PI3 K, p38 MAPK , and MEK suppressed IL-18 plus IFN-gamma induced CXCL9, CXCL10 , and CXCL11 production and NF-kappaB, STAT1, and IRF-1 activities
Hung et al., Pediatr Allergy Immunol 2007 : The suppressive effect on MDC and IP-10 may, at least in part, involve the down-regulation of LPS induced p38 and ERK-MAPK expression
Petrai et al., Int J Biochem Cell Biol 2008 : In human microvascular endothelial cells, which selectively express CXCR3-B, in a cell cycle dependent fashion, CXCL10 and CXCL4 increased the enzymatic activity of p38 ( MAPK )
Lee et al., J Immunol 2008 : The p38 and ERK pathway inhibitors SB203580 and U0126 reversed the repressive effect of IL-17 on CXCL10 mRNA abundance and promoter activity and also reversed the inductive effect of IL-17 on CXCL8 mRNA, indicating that MAPK signaling mediates both the transcriptional repression of CXCL10 and the stabilization of CXCL8 mRNA by IL-17
Cao et al., Microbes Infect 2010 (Pneumococcal Infections) : Both PspA and PspC could activate p38 MAPK and NF-?B pathways in neutrophils, while inhibition of NF-?B and p38 MAPK could suppress the release of CXCL8 from neutrophils induced by PspA and PspC. Together, our results demonstrated that the induction of CXCL8 in human neutrophils activated by PspA and PspC was regulated by p38 MAPK and NF-?B pathways
Dogan et al., Microbes Infect 2011 : Pneumolysin induced CXCL8 production by nasopharyngeal epithelial cells is dependent on calcium flux and MAPK activation via Toll-like receptor 4
Tsai et al., J Investig Med 2011 (Inflammation...) : Only extracellular signal regulated kinases and c-Jun N-terminal kinases (JNK) mitogen activated protein kinase inhibitors suppressed LPS induced IP-10 expression
Chen et al., Molecular vision 2011 : Inhibition of p38MAPK , phosphoinositide 3-kinase (PI3K)-Akt and nuclear factor-kappaB ( NF-?B ), with the inhibitors SB203580, LY294002 and pyrrolydine dithiocarbamate ( PDTC ) respectively, reduced IL-17 ( 100 ng/ml ) mediated production of CXCL8 , CCL2, and IL-6 in a concentration dependent manner
Dumitru et al., J Leukoc Biol 2012 (Head and Neck Neoplasms...) : Most importantly, HNC induced p38-MAPK activation strongly stimulates the release of CCL4, CXCL8 , and MMP9 by neutrophils
Liu et al., PloS one 2012 (Carotid Artery Injuries) : Moreover, p38 MAPK was involved in suppression of CCL5 and IP-10 expression in SMCs through common upstream molecule MKK3 ... Our findings indicate that CCL5 induction in aorta and SMCs is mediated by IRF-1 while activation of p38 MAPK signaling inhibits CCL5 and IP-10 expression
Alrashdan et al., Am J Physiol Lung Cell Mol Physiol 2012 (Asthma) : We aimed to investigate the role of cytokine induced MAPK activation in CXCL10 production by ASM cells from people with and without asthma
Seidel et al., Eur Respir J 2013 : DMF inhibited CXCL10 secretion and increased HO-1 levels, and p38 mitogen activated protein kinase ( MAPK ) inhibition reduced DMF dependent HO-1 expression ... In human primary ASMCs, DMF inhibits CXCL10 secretion by reducing the cellular glutathione level and by activation of p38 MAPK and HO-1