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MAPK7 — PLD2
Text-mined interactions from Literome
Min et al., Exp Mol Med 2002
(MAP Kinase Signaling System) :
Interestingly, specific inhibition of p38
MAPK with SB203580
attenuated pervanadate induced
PLD activation
Cummings et al., Mol Cell Biochem 2002
:
In pulmonary epithelial and vascular endothelial cells, a wide variety of agonists stimulate
PLD and
involve Src kinases, p-38
mitogen activated protein kinase , calcium and small G proteins
Grab et al., Biochim Biophys Acta 2004
:
Differential
role for
phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate stimulated
MAPK activation, Cox-2 and IL-8 expression ... Differential
role for phospholipase D1 and
phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate stimulated
MAPK activation, Cox-2 and IL-8 expression
Fernández-Tome et al., Biochem Biophys Res Commun 2004
:
p44/42 ( ERK1/2 )
MAPK and
PLD activation by PGD2 preserves papillary phosphatidylcholine homeostasis
Li et al., J Pharmacol Exp Ther 2005
:
These data indicate that Ang II-stimulated Akt activity is mediated by cPLA(2) dependent, p38
MAPK regulated
PLD(2) activation and EGFR transactivation
Hamdi et al., Biochim Biophys Acta 2008
(MAP Kinase Signaling System) :
As a functional consequence of this
PLD2 dependent
MAPK activation, interleukin-2 production evoked by PMA/ionomycin stimulation or CD3/CD28 engagement was enhanced in the two T-cell lines overexpressing PLD2
Park et al., J Biol Chem 2009
:
Der f 2-induced
PLD activation was
attenuated by PLCgamma inhibitors ( U73122 and PAO ), PKCalpha inhibitors ( RO320432 and GO6976 ), and p38
MAPK inhibitors ( SB203580 and SB202190 )
Cho et al., Mol Cell Biol 2011
:
In contrast, ectopic expression of wild-type
PLD2 enhanced Ras and
MAPK activation in response to therapeutic levels of lovastatin
Ito et al., J Neurochem 1998
:
Possible
involvement of
mitogen activated protein kinase in
phospholipase D activation induced by H2O2, but not by carbachol, in rat pheochromocytoma PC12 cells