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MAPK7 — TERF2

Text-mined interactions from Literome

Mochizuki et al., Nature 1999 : This decrease in GTP bound Rap1 activates ERK/MAPK
Palsson et al., J Biol Chem 2000 : Furthermore, constitutively active Rap1AV12 inhibited p38 MAPK activation by IL-1, consistent with Rap antagonizing Ras function
Pizon et al., Oncogene 2000 (MAP Kinase Signaling System) : Although the role of Rap1A in MAPK activation has been analysed in various cell types, the signalling pathways activated by Rap1A have not been explored in myogenic cells
Kievit et al., Mol Endocrinol 2001 (Pituitary Neoplasms) : These findings provide evidence for a model for cAMP induced PRL transcription involving Rap1 induced MAPK activity leading to stimulation of the transcriptional coactivators, CBP and p300
McDermott et al., J Biol Chem 2002 : In the same manner, the inhibitory effect of Rap on the activation of p38 by IL-1 occurred at a point downstream of MyD88, IRAK, and TRAF6, since the activation of p38 MAPK by these components was inhibited by overexpressing active Rap1AV12 , while neither MKK3 nor MKK6 were affected
Huang et al., J Biol Chem 2004 (MAP Kinase Signaling System) : Rap1 induced p38 mitogen activated protein kinase activation facilitates AMPA receptor trafficking via the GDI.Rab5 complex
Chen et al., Mol Microbiol 2005 (MAP Kinase Signaling System) : The Rap-1 inhibitor, GGTI-298, restored MAPK activation in the presence of cAMP, further suggesting that Rap-1 is responsible for cAMP dependent MAPK inhibition
Stork et al., Blood 2005 : Rap1 may also regulate cellular differentiation and proliferation via pathways that are distinct from those mediating adhesion, and involve regulation of the mitogen activated protein ( MAP ) kinase or ERK ( extracellular signal regulated kinase ) cascade
Karhoff et al., Neuroendocrinology 2007 (Digestive System Neoplasms...) : In endocrine cells, the small G-protein Rap1 stimulates mitogen activated protein kinase ( MAPK ) signaling by activating B-Raf
Minato et al., Adv Immunol 2007 (Neoplasms) : Rap1 also regulates MAP kinase ( MAPK ) activity in a manner highly dependent on the context of cell types
Stadtmann et al., Eur J Immunol 2011 (Peritonitis) : Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin dependent slow leukocyte rolling ... Our data demonstrate that Rap1a activation by p38 MAPK and CalDAG-GEFI is involved in E-selectin dependent slow rolling and leukocyte recruitment