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IL12B — PPARG
Text-mined interactions from Literome
Gosset et al., Eur J Immunol 2001
:
Moreover, activation of
PPARgamma resulted in a dramatic decreased secretion of the Th1 promoting factor
IL-12 in LPS- and CD40L stimulated cells ( by 47 % and 62 % ), while the production of IL-1beta, TNF-alpha, IL-6 and IL-10 was unaffected
Klotz et al., J Immunol 2007
:
Sustained
PPARgamma activation in murine DCs
reduced maturation induced expression of costimulatory molecules and
IL-12 , and profoundly inhibited their capacity to prime naive CD4 ( + ) T cells in vitro