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SOX10 — TCF7
Text-mined interactions from Literome
Jiao et al., Pigment Cell Res 2004
:
These results suggest that a combinatorial transcription factor interaction is important for expression of Dct in neural crest derived melanocytes, and support a model for sequential gene activation in melanocyte development whereby Mitf, a
Sox10 dependent
transcription factor , is expressed initially before an early melanocyte differentiation gene, Dct, is expressed
Passeron et al., Proc Natl Acad Sci U S A 2007
:
During melanocyte development from the neural crest,
SOX10 regulates microphthalmia associated
transcription factor , which controls a set of genes critical for pigment cell development and pigmentation, including dopachrome tautomerase and tyrosinase ... In adult and neonatal melanocytes,
SOX9 regulates microphthalmia associated
transcription factor , dopachrome tautomerase, and tyrosinase promoters, leading to an increase in the expression of these key melanogenic proteins and finally to a stimulation of pigmentation
Chen et al., Liver Int 2013
(Carcinoma, Hepatocellular...) :
In addition,
SOX4 in HepG2 cell can
enhance ß-catenin/TCF activity by increasing ß-catenin level