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IL1RN — IL2
Text-mined interactions from Literome
Mühlberg et al., J Clin Endocrinol Metab 2000
(Graves Disease) :
Recent data have indicated that orbital fibroblasts ( OF ) can be stimulated to produce marked quantities of
interleukin-1 receptor antagonist ( IL-1RA ), a powerful
inhibitor of the proinflammatory activities of
interleukin-1 in the orbital tissues in Graves ' ophthalmopathy ( GO )
Verheyen et al., Immunol Invest 2001
:
IL-1 and
IL-1 receptor antagonist (IL-1Ra) were
up-regulated by
IL-2 , this was achieved independently of IL-12 or CD40/CD40L interaction
Kovár et al., Parasitol Res 2002
:
ELISA ( protein level ) and RNAse protection assay ( mRNA level ) showed that SGE
enhanced interleukin (IL)-1alpha, IL-1beta,
IL-1Ra , IL-6, and IL-12p40 cytokines, whereas production of
IL-2 , IL-5, IL-10, and IL-13 was decreased
Conti et al., Int J Immunopharmacol 1992
(Leukemia, T-Cell) :
The enhancing
effect of
IL-1ra on
IL-2 activity was similar to that provoked by IL-1 beta
Cominelli et al., Gastroenterology 1992
(Colitis) :
Recombinant
interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous
interleukin-1 in rabbit immune colitis
Burger et al., J Clin Invest 1995
:
The inhibitory activity of human
interleukin-1 receptor antagonist is
enhanced by type II
interleukin-1 soluble receptor and hindered by type I interleukin-1 soluble receptor
Du Bois et al., J Clin Oncol 1997
(Carcinoma, Renal Cell...) :
IL-2 induced TNF bioactivity, neutrophil chemotactic defect, and serum IL-6, IL-8, and
IL-1 receptor antagonist (IL-1RA) induction were suppressed by rhuTNFR : Fc