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ANGPT2 — OLR1

Text-mined interactions from Literome

Chen et al., Biochem J 2006 (Atherosclerosis) : Furthermore, this study suggests that while ox-LDL and Ang II both induce LOX-1 expression in HCAECs, the underlying mechanisms of promoter activation are different from each other
Chen et al., Arterioscler Thromb Vasc Biol 2006 : The Ang II ( 1 micromol/L for 24 hours ) markedly induced LOX-1 promoter activity beyond the basal level, and a 116-bp fragment ( between nt -2247 and -2131 ) was necessary for this induction ... This study strongly suggests that Ang II , by activating NF-kappaB, induces LOX-1 promoter activation
Hu et al., Hypertension 2007 : Ang II via type 1 receptor upregulates the expression of LOX-1 , a lectin-like receptor for oxidized low-density lipoprotein ... These findings suggest that small concentrations of Ang II promote capillary formation by inducing the expression of VEGF via Ang II type 1 receptor/LOX-1 mediated stimulation of the reactive oxygen species-mitogen activated protein kinase pathway
Rudijanto et al., Acta Med Indones 2007 (Arteriosclerosis...) : LOX-1 expression increased also through oxygen species ( ROS ), endothelin-1 (ET-1), tumor necrosis factor-alpha (TNF-alpha), shear stress, activation of protein kinase-C ( PKC ), angiotensin-II (ANG-II) , and through inflammatory pathways
Wang et al., Inflamm Res 2013 (Inflammation) : Ang II also induced LOX-1 expression in human ECs and rabbit aortic ECs
Wang et al., Experimental biology and medicine (Maywood, N.J.) 2012 (Inflammation) : The selective inhibitors of MAPKs, c-Jun and NF-?B each blocked the transcription of LOX-1 and pro-inflammatory genes in response to Ang II as well as LPS