Gene interactions and pathways from curated databases and text-mining

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HMGB1 — TGFB1

Text-mined interactions from Literome

El Gazzar et al., Inflamm Res 2007 (Inflammation) : LPS induced HMGB1 release at 8 h and reached a peak at 48 h. Significant ( p < 0.05 ) production of TNFalpha, IL-1beta, IL-10, and TGF-beta1 was seen after 8 h
Lenga et al., Circ Res 2008 (Fibrosis) : Treatment of wild-type cells with small interfering RNA to knock down OPN reduced transforming growth factor-beta1 induced alpha-smooth muscle actin and HMGB1 to levels observed in OPN-null cells