Gene interactions and pathways from curated databases and text-mining

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IRF1 — MTOR

Text-mined interactions from Literome

Fielhaber et al., J Biol Chem 2009 : The regulation of IRF-1 or caspase-1 by mTOR was independent of other known mTOR effectors p70 S6 kinase and Akt
Zhang et al., Mol Med 2012 (Endotoxemia) : In contrast, overexpression of IRF-1 alone increased the activation of mTOR and consequently decreased autophagic flux