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CASP3 — TET2

Text-mined interactions from Literome

Lai et al., J Immunol 2001 : Moreover, we found that Tet- and Tripterygium wilfordii hook F-induced T cell DNA damage required caspase-3 activity, and hydroxychloroquine induced T cell DNA damage was mediated through a caspase-3- and caspase-8 independent, but Z-Asp-Glu-Val-Asp-fluomethyl ketone-sensitive, signaling pathway
Raymond et al., Experimental biology and medicine (Maywood, N.J.) 2004 : The following effects were observed : ( i ) TET reduced both cell growth and viability only in the presence of ascorbate or alpha-tocopherol ; ( ii ) TET reduced CCO activity and increased mitochondrial ROS production as indicated by increased expression of Mn super-oxide dismutase, but the induction of Mn superoxide dismutase was not affected by ascorbate or alpha-tocopherol ; ( iii ) TET acted independently of ascorbate or alpha-tocopherol in disrupting mitochondrial membrane potential ; ( iv ) TET did not increase caspase-8 activity in the absence of ascorbate or alpha-tocopherol ; and ( v ) TET did not increase transfer of cytochrome c from mitochondria to the cytosol unless alpha-tocopherol was present