◀ Back to MAPK12

MAPK12 — RABEPK

Text-mined interactions from Literome

Ma et al., J Immunol 2004 : A role for c-Jun N-terminal kinase (JNK) MAPK in LPS induced IL-12p40 regulation in a promonocytic THP-1/CD14 cell line was demonstrated by using specific inhibitors of JNK activation, SP600125 and a dominant negative stress activated protein/extracellular signal regulated kinase kinase-1 mutant
Ichikawa et al., Biol Pharm Bull 2004 : These results suggest that gallate containing catechins, particularly EGCG, inhibits LPS induced IL-12p40 production in murine macrophages by inhibiting p38 MAPK while enhancing p44/p42 ERK, leading to the inhibition of IkappaBalpha degradation and NF-kappaB activation
Mitchell et al., J Infect Dis 2010 : IL-12p40 was significantly inhibited by both p38 mitogen activated protein kinase ( MAPK ) and extracellular signal regulated kinase inhibitors, whereas IL-12p70 was inhibited by p38 MAPK inhibitor alone