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MAPK12 — SRPK1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Hayes et al., Cancer Res 2007
(Breast Neoplasms...) :
Consequently, we have shown that targeted inhibition of
SRPK1 in tumor cells
results in reduced phosphorylation of MAPK3,
MAPK1 , and AKT
Odunsi et al., PloS one 2012
(Carcinoma...) :
Reduction of
SRPK1 expression using small interfering RNA ( siRNA ) encoding small hairpin RNA in ovarian cancer cells
led to ( i ) reduced cell proliferation rate, slower cell cycle progression and compromised anchorage independent growth and migration ability in vitro, ( ii ) decreased level of phosphorylation of multiple serine-arginine proteins, and
P44/42MAPK and AKT proteins, and ( iii ) enhanced sensitivity to cisplatin