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PRKAB1 — PRKAR2B

Text-mined interactions from Literome

Mao et al., Exp Cell Res 2004 : Finally, in CHO cells overexpressing wild-type MLTKalpha, no activation of AMPK of PKA could be demonstrated, indicating that the activated kinase cascades are not involved in a cross-talk process
Gauthier et al., J Biol Chem 2008 : Likewise, small hairpin RNA mediated silencing of adipose tissue triglyceride lipase inhibited both forskolin stimulated lipolysis and AMPK activation but not that of PKA
Omar et al., Cell Signal 2009 : Taken together, these data suggest that PDE3B and PDE4 regulate cAMP pools that affect the activation/phosphorylation state of AMPK and that the effects of cyclic AMP on AMPK involve Epac1, PKA and lipolysis
Djouder et al., EMBO J 2010 : These results suggest a new mechanism of negative regulation of AMPK activity by PKA that is important for converting a lipolytic signal into an effective lipolytic response
Pulinilkunnil et al., J Biol Chem 2011 : Both PKA and AKT inhibitors attenuated AMPK Ser ( 485/491 ) phosphorylation resulting from a-adrenergic blockade and prevented decreases in AMPK activity
Liu et al., Biochimie 2012 : Adiponectin levels are also stimulated by FOXO1 and AMP activated protein kinase (AMPK) , and are suppressed by PKA or silencing mediator of retinoid and thyroid hormone receptors ( SMRT )
Damm et al., Mol Endocrinol 2012 (MAP Kinase Signaling System) : Melanocortin induced PKA activation inhibits AMPK activity via ERK-1/2 and LKB-1 in hypothalamic GT1-7 cells ... Inhibitory effects of a-MSH on AMPK were blocked by specific inhibitors of protein kinase A (PKA) or ERK-1/2, pointing to an important role of both kinases in this process
Nin et al., J Biol Chem 2012 : In fact, an increase in cAMP/PKA activity resulted in the dissociation of SIRT1 and DBC1 in an AMP activated protein kinase (AMPK) dependent manner
Stone et al., Frontiers in physiology 2012 : Interestingly, AICAR also phosphorylated a suspected PKA-inhibitory Ser485 site on AMPK, and these cumulative events were reversed by the PKA inhibitor PKI suggesting possible PKA mediated regulation of AMPK ... The cAMP stimulator forskolin increased PKA activity and completely ameliorated Ser/Thr protein phosphatase-2C activity, suggesting a potential mechanism of AMPK modulation by PKA since inhibition of PKA by PKI reduced AMPK activity