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TCF7 — TNFSF11
Text-mined interactions from Literome
Shen et al., Biochim Biophys Acta 2007
:
Both of these putative promoters were responsive to the osteoclast inducing cytokine, receptor activator of NF-kappaB ligand ( RANKL ) and demonstrated trans-activation by the
RANKL induced
transcription factor nuclear factor of activated T cells ( NFATc1 ), consistent with a role in regulating CTR gene expression in osteoclasts
Kim et al., Mol Nutr Food Res 2012
(Bone Resorption) :
RANKL induced activation of nuclear factor of activated T cells c1 ( NFATc1 ) and microphthalmia associated
transcription factor was also suppressed by phloretin
Kim et al., Biochem Pharmacol 2013
(Bone Resorption) :
Trapidil reduced
RANKL induced expression of nuclear factor of activated T cells, cytoplasmic 1 ( NFATc1 ), a master
transcription factor for osteoclastogenesis, without affecting the expression of c-Fos that functions as a key upstream activator of NFATc1 during osteoclastogenesis