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TCF7 — TYR

Text-mined interactions from Literome

Englaro et al., Oncogene 1999 (Melanoma, Experimental) : Indeed, overexpression of this transcription factor in B16 cells is sufficient to inhibit tyrosinase promoter activity
Galibert et al., EMBO J 2001 (Melanoma) : The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression
Aoki et al., Life Sci 2002 : The microphthalmia associated transcription factor ( MITF ), which belongs to the family of bHLH-LZ type transcription factors, regulates the transcription of melanogenesis related enzyme genes such as the tyrosinase and TRP-1 genes
Shimoda et al., Biol Pharm Bull 2010 (Melanoma, Experimental) : In addition, MS-818 ( 100 microM ) markedly inhibited melanogenesis in B16 melanoma cells via downregulation of tyrosinase expression mediated by microphthalmia associated transcription factor ( MITF ) and extracellular signal regulated kinase ( ERK )
Diwakar et al., Fitoterapia 2012 : Siberian larch and pomegranate fruit extracts inhibited expression of melanocyte specific genes, tyrosinase (Tyr), microphthalmia transcription factor ( Mitf ), and melanosome structural proteins ( Pmel17 and Mart1 ) but did not inhibit tyrosinase enzyme activity
Yen et al., Evidence-based complementary and alternative medicine : eCAM 2012 : Further, PNM exhibited a significant antimelanogenesis effect ( P < 0.05 ) by reducing the levels of phospho-cAMP response element binding protein and microphthalmia associated transcription factor ( MITF ), inhibiting the synthesis of tyrosinase , tyrosinase related protein-1 (TRP-1), and TRP-2, and decreasing the cellular melanin content
Fuse et al., Biochem Biophys Res Commun 1996 (Melanoma...) : Microphthalmia associated transcription factor ( MITF ), the human homolog of the mouse microphthalmia gene product, regulates melanocyte-specific transcription of the tyrosinase gene that codes for an essential enzyme in melanin biosynthesis