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LIPE — PPARG

Text-mined interactions from Literome

Deng et al., Endocrinology 2006 : We demonstrate that expression of the HSL gene is up-regulated by PPARgamma and PPARgamma agonists ( rosiglitazone and pioglitazone ) in the cultured hepatic cells and differentiating preadipocytes ... In addition, mithramycin A, the specific inhibitor for Sp1-DNA binding activity, abolishes the PPARgamma mediated up-regulation of HSL ... These results indicate that PPARgamma positively regulates the HSL gene expression, and up-regulation of HSL by PPARgamma requires the involvement of Sp1
Yajima et al., Biochem Biophys Res Commun 2007 : These results indicate that the HSL gene is transcriptionally regulated by PPARgamma/RXRalpha heterodimer, and suggest that a cis acting element regulates the HSL gene expression