Ahi et al., Behav Brain Res 2004
:
Inhibition of PKA impaired context- and tone dependent fear conditioning and significantly reduced the phosphorylation of Elk-1, p90Rsk-1 , Erk-1/2, and CREB
Constantinescu et al., J Biol Chem 2004
(MAP Kinase Signaling System) :
This mechanism appears to involve type I PKA dependent phosphorylation of CBP and inhibition of MEK dependent phosphorylation of p90RSK