◀ Back to PARP8
EPHB2 — PARP8
Text-mined interactions from Literome
Weiderhold et al., Int J Cancer 2006
(Mammary Neoplasms, Animal) :
Bcl-2 phosphorylation and
activation of
ERK and JNK and caspase 3-dependent cleavage of
PARP were observed in MDA-MB-435 cells treated with CB694
Lee et al., J Neurochem 2009
(Neuroblastoma) :
Furthermore, inhibition of
ERK reduced ONE induced phosphorylation of p53, a key modulator of the cellular stress response, and the proteolytic cleavage of poly ( ADP-ribose ) polymerase (
PARP ), a hallmark of apoptosis
Gatson et al., Journal of neuroinflammation 2009
(Burns...) :
In addition, we determined that in the estrogen treated rats there was an increase in the levels of
phospho-ERK ( p < 0.01 ) and Akt ( p < 0.05 ) at the 24 hour time-point, and that 17 beta-estradiol
blocked the activation of caspase-3 ( p < 0.01 ) and subsequent cleavage of
PARP ( p < 0.05 )
Zeng et al., J Ethnopharmacol 2010
:
In addition, MWG extract attenuated activation of caspase-3 and
poly ADP-ribose polymerase ( PARP ) and
inhibited the phosphorylation of
ERK , c-Jun NH ( 2 ) -terminal kinase ( JNK ) and p38 MAPKs