UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to CREBBP

CREBBP — POLR2A

Pathways - manually collected, often from reviews:

BioCarta the information processing pathway at the ifn beta enhancer: IFN-beta nucleosome complex (RELA-ATF2-IRF5_IRF1_IRF3_IRF6_IRF7_IRF4_IRF2-JUN-HMGB1-PCAF-CREBBP-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) → TAFs/TF2A/TBP/TF2F/TF2B/TF2H/TF2E/RNA POL II complex (GTF2A1-NR3C1-GTF2F1-GTF2B-GTF3A-GTF2E1-POLR2A) (modification, collaborate)
BioCarta the information processing pathway at the ifn beta enhancer: RELA/p50/ATF-2/IRF/c-JUN/HMG1/PCAF/CBP/hSWI/SNF complex (RELA-ATF2-IRF5_IRF1_IRF3_IRF6_IRF7_IRF4_IRF2-JUN-HMGB1-PCAF-CREBBP-SMARCA4-SMARCD1-ARID1A-SMARCC1-SMARCC2-SMARCB1-SMARCE1-ACTB) → TAFs/TF2A/TBP/TF2F/TF2B/TF2H/TF2E/RNA POL II complex (GTF2A1-NR3C1-GTF2F1-GTF2B-GTF3A-GTF2E1-POLR2A) (modification, collaborate)
BioCarta carm1 and regulation of the estrogen receptor: Estrogen/ER alpha/Estrogen/ER alpha/GRIP1/CARM1/p300(Me)/CBP(Me) complex (CARM1-EP300-CREBBP-GRIP1-ESR1) → TF2A/TAFs/TBP/TF2F/TF2H/RNA Pol II/TF2E complex (POLR2A-GTF2F1-GTF3A-GTF2A1-GTF2E1-NR3C1) (transcription, activates)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: CREBBP — POLR2A (physical association, affinity chromatography technology) Cho et al., Mol Cell Biol 1998
IRef Biogrid Interaction: CREBBP — POLR2A (colocalization, biochemical) Cho et al., Mol Cell Biol 1998
MIPS CORUM HES1 promoter corepressor complex: HES1 promoter corepressor complex complex (CDK7-CREBBP-EP300-POLR2A-RBPJ-SUPT6H) Fryer et al., Mol Cell 2004
MIPS CORUM RNA polymerase II complex (CBP, PCAF, RPB1, BAF47, CYCC, CDK8), chromatin structure modifying: RNA polymerase II complex (CBP, PCAF, RPB1, BAF47, CYCC, CDK8), chromatin structure modifying complex (CCNC-CDK8-CREBBP-KAT2B-POLR2A-SMARCB1) Cho et al., Mol Cell Biol 1998
MIPS CORUM RNA polymerase II complex, incomplete (CBP, RPBI, PCAF, BAF47), chromatin structure modifying: RNA polymerase II complex, incomplete (CBP, RPBI, PCAF, BAF47), chromatin structure modifying complex (CREBBP-KAT2B-POLR2A-SMARCB1) Cho et al., Mol Cell Biol 1998
MIPS CORUM RNA polymerase II complex, chromatin structure modifying: RNA polymerase II complex, chromatin structure modifying complex (CCNC-CDK8-CREBBP-ERCC3-GTF2B-GTF2F1-GTF2H3-MED21-KAT2B-POLR2A-SMARCA2-SMARCA4-SMARCB1) Cho et al., Mol Cell Biol 1998
MIPS CORUM MASH1 promoter-coactivator complex: MASH1 promoter-coactivator complex complex (CREBBP-HES1-HIST1H4C-HIST1H4B-HIST1H4A-HIST4H4-HIST1H4F-HIST1H4E-HIST1H4D-HIST1H4K-HIST1H4J-HIST1H4I-HIST1H4H-HIST1H4L-HIST2H4B-HIST2H4A-NONO-PARP1-KAT2B-POLR2A-SRC-H3F3B-H3F3A-HIST1H3B-HIST1H3C-HIST1H3A-HIST1H3F-HIST1H3G-HIST1H3D-HIST1H3E-HIST1H3J-HIST1H3H-HIST1H3I-HIST2H3D-HIST2H3C-HIST2H3A) Ju et al., Cell 2004
MIPS CORUM CAMK2-delta-MASH1 promoter-coactivator complex: CAMK2-delta-MASH1 promoter-coactivator complex complex (CAMK2D-CREBBP-HES1-NONO-PARP1-KAT2B-POLR2A-SRC) Ju et al., Cell 2004
IRef Corum Interaction: Complex of CCNC-POLR2A-CDK8-SMARCB1-CREBBP-KAT2B (association, ion exchange chromatography) Cho et al., Mol Cell Biol 1998
IRef Corum Interaction: Complex of 23 proteins (association, chromatin immunoprecipitation assay) Ju et al., Cell 2004
IRef Corum Interaction: Complex of POLR2A-POLR2A-SMARCB1-SMARCB1-CREBBP-KAT2B-CREBBP-KAT2B (association, far western blotting) Cho et al., Mol Cell Biol 1998
IRef Corum Interaction: Complex of CAMK2D-POLR2A-SRC-PARP1-HES1-KAT2B-CREBBP-NONO (association, chromatin immunoprecipitation assay) Ju et al., Cell 2004
IRef Corum Interaction: Complex of 27 proteins (association, far western blotting) Cho et al., Mol Cell Biol 1998
IRef Corum Interaction: Complex of CDK7-POLR2A-EP300-RBPJ-CREBBP-SUPT6H (association, chromatin immunoprecipitation assay) Fryer et al., Mol Cell 2004
IRef Hprd Interaction: CREBBP — POLR2A (in vitro) Cho et al., Mol Cell Biol 1998
IRef Hprd Interaction: CREBBP — POLR2A (in vivo) Cho et al., Mol Cell Biol 1998
IRef Ophid Interaction: POLR2A — CREBBP (aggregation, confirmational text mining) Cho et al., Mol Cell Biol 1998
IRef Ophid Interaction: POLR2A — CREBBP (aggregation, interologs mapping) Brown et al., Bioinformatics 2005