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GIP — MAPK10

Text-mined interactions from Literome

Ehses et al., Endocrinology 2003 : Thus, these data suggest that GIP is able to regulate INS-1 cell survival by dynamic control of p38 MAPK phosphorylation via cAMP signaling and lend further support to the notion that GIP regulation of MAPK signaling is critical for its regulation of cell fate
Kim et al., J Biol Chem 2007 (MAP Kinase Signaling System...) : Chronic elevation of circulating GIP levels in the Vancouver Diabetic Fatty ( VDF ) Zucker rat resulted in increases in circulating resistin levels and activation of p38 MAPK or SAPK/JNK in epididymal fat tissue, suggesting the existence of identical pathways in vivo as well as in vitro
Widenmaier et al., J Biol Chem 2009 : Importantly, we discovered that GIP suppressed p38 MAPK and JNK via Akt mediated changes in the phosphorylation state of the apoptosis signal regulating kinase 1 in INS-1 cells and human islets, resulting in inhibition of its activity
Angevine et al., Nutrition & diabetes 2012 : Inhibition of GIP expression by the PI3/AKT inhibitor, LY294002, was abrogated in STC-1 cells with reduced menin levels, whereas the MAPK inhibitor, UO126, inhibited the expression of GIP independent of menin
Chabre et al., J Clin Endocrinol Metab 1998 (Adenoma...) : In quiescent cells, GIP and ACTH stimulated [ 3H ] thymidine incorporation and p42-p44 mitogen activated protein kinase activity