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AHSA1 — IL8

Text-mined interactions from Literome

Hashimoto et al., Eur Respir J 1999 : The aim of this study was to examine the role of p38 mitogen activated protein ( MAP ) kinase in interleukin (IL)-8 expression in tumour necrosis factor (TNF)-alpha- and IL-1alpha stimulated human pulmonary vascular endothelial cells
Arbabi et al., Arch Surg 1999 : It seems that p38 activation is necessary but not sufficient for IL-8 production by human mononuclear cells
Hippenstiel et al., Blood 2000 : Using human umbilical vein endothelial cells ( HUVECs ), we analyzed the role of small GTP binding Rho proteins and p38 mitogen activated protein kinase ( MAPK ) for LPS dependent IL-8 expression in endothelial cells
Na et al., Int Immunopharmacol 2001 : Collectively, this series of experiments indicates that radicicol inhibits IL-8 gene expression by blocking ERK1/2 and p38 signaling
Kehlen et al., Clin Exp Immunol 2002 (Arthritis, Rheumatoid...) : The MAPK p38 appears necessary for the regulation of IL-8 , GRO-alpha and GRO-beta expression as shown by inhibition with SB203580
Jijon et al., Am J Physiol Cell Physiol 2002 : In this study we examined the roles of extracellular signal regulated kinase ( ERK ) and p38 in the expression of interleukin-8 (IL-8) and intercellular adhesion molecule-1 ( ICAM-1 ) using the human intestinal cell line HT-29
Ameixa et al., Infect Immun 2002 (MAP Kinase Signaling System) : Interleukin-8 secretion from Mycobacterium tuberculosis infected monocytes is regulated by protein tyrosine kinases but not by ERK1/2 or p38 mitogen activated protein kinases
Furuichi et al., Respirology 2002 (Asthma, Exercise-Induced...) : p38 mitogen activated protein kinase and c-Jun-NH2-terminal kinase regulate interleukin-8 and RANTES production in hyperosmolarity stimulated human bronchial epithelial cells
Németh et al., Am J Pathol 2002 (MAP Kinase Signaling System) : Hyperosmolarity activated both p38 and p42/44 mitogen activated protein kinases, which effect contributed to hyperosmolarity stimulated IL-8 production, because p38 and p42/44 inhibition prevented the hyperosmolarity induced increase in IL-8 production
Bian et al., Exp Eye Res 2003 (Translocation, Genetic) : In addition, anti-inflammatory drugs dexamethasone ( DEX ) and cyclosporin A ( CSA ) both blocked activation of JNKS/SAPK and the cell-cell contact induced production of hRPE IL-8 and MCP-1, while activation of p38 and ERK was only inhibited by DEX, but not by CSA
Grab et al., Biochim Biophys Acta 2004 : The ERK and p38 MAPKs can also stimulate the expression of both cyclooxygenase-2 (Cox-2) and interleukin-8 (IL-8)
Kim et al., Biochem Biophys Res Commun 2004 (MAP Kinase Signaling System) : Differential regulation of IGF-II induced IL-8 by extracellular signal regulated kinase 1/2 and p38 mitogen activated protein kinases in human keratinocytes
Liboni et al., Cytokine 2004 : The p38 inhibitor SB 203580 resulted in a significant decrease in IL-8 peptide production ( p < 0.01 )
Khan et al., Immunology 2004 : Collectively, our results suggest that TLR5 mediates p38 MAPK dependent IL-8 secretion from epithelial and monocytic cells incubated with FliC-EAEC, and that this effect requires IL-8 promoter activation independent of NF-kappaB nuclear migration
Kim et al., Eur J Immunol 2005 (Bacteroides Infections...) : The p38 inhibitor SB203580 and the ERK inhibitor U0126 reduced not only AP-1 activity, but also decreased IL-8 and MCP-1 expression
Moorman et al., Respir Res 2005 : Treatment with HCV core led to phosphorylation of p38 MAPK, and expression of IL-8 was dependent upon p38 activation
Kim et al., Int Immunol 2005 (MAP Kinase Signaling System) : Exposure of the cells to CpG ODN resulted in a time- and dose dependent increase of IL-8 expression, and activation of phosphorylated ERK1/2 and phosphorylated p38
Islam et al., Toxicol Appl Pharmacol 2006 : Taken together, these data suggest that ( 1 ) p38 activation was required for induction of IL-8 and proinflammatory gene expression in the monocyte and ( 2 ) DON induced p38 activation in human monocytes via the ribotoxic stress response
Opitz et al., J Immunol 2006 : Finally, L. monocytogenes- and Nod1 induced IL-8 production was blocked by a specific p38 inhibitor
He et al., Mol Immunol 2007 (Inflammation...) : Furthermore, we show p38MAPK activation is necessary for increased VEGF and IL-8 secretion, NF-kappaB activation contributes to apoptosis resistance of human lung cancer cells induced by LPS
Subramanian et al., Inflamm Bowel Dis 2008 (Colonic Neoplasms...) : IL-8 release was mediated by extracellular regulated kinase (ERK) and p38 mitogen activated protein kinase ( MAPK ) and inhibited by mesalamine, but not hydrocortisone, at therapeutic concentrations
Min et al., Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008 (MAP Kinase Signaling System...) : Furthermore, inhibition of the ERK, p38 , and NF-kappaB pathways blocked SNP induced IL-8 secretion
Regueiro et al., Eur Respir J 2009 : LBP and sCD14 inhibited the nontypeable Haemophilus influenzae ( NTHi ) -dependent secretion of IL-8 and the activation of NF-kappaB and p38 mitogen activated protein kinase signalling pathways but they increased the internalisation of NTHi by airway epithelial cells
Ebert et al., Am J Physiol Gastrointest Liver Physiol 2009 (MAP Kinase Signaling System) : IL-8 production by either cell type involved phosphorylation of p38 and JNK
Wu et al., Chest 2009 (Pneumonia, Ventilator-Associated...) : The selective p38 and JNK inhibitors, as well as dexamethasone, successfully inhibited IL-8 production
Nomi et al., Invest Ophthalmol Vis Sci 2010 : The zymosan induced release of IL-6 and IL-8 was attenuated by inhibitors of ERK, p38 , JNK, and NF-kappaB signaling
Suzuki et al., J Periodontal Res 2010 (Periodontitis) : The p(38) MAPK inhibitors SB203580 and SB202190 and the ERK inhibitor PD98059 inhibited the OxLDL induced IL-8 production
Riesenhuber et al., Perit Dial Int 2011 (Inflammation) : Effects of p38 on IL-8 were at transcriptional, posttranscriptional, and translational levels
Okogbule-Wonodi et al., Dig Liver Dis 2012 : C-Jun N-terminal kinase, p38 and NF-?B inhibitors significantly attenuated LPS stimulated IL-8 production by 42 %, 33 % and 2 %, respectively
Wawszczyk et al., Acta Pol Pharm 2012 (MAP Kinase Signaling System) : The findings of this study show that p38 MAPK could be one of the molecular targets for IP6 in the intestinal epithelial cells and that IP6 inhibitory effect on IL-8 secretion by Caco-2 cells could be mediated by its inhibition of p38 activity
Shan et al., J Gastroenterol Hepatol 2013 : Inhibition of p38 mitogen activated protein kinase ( p38 MAPK ) and protein kinase A (PKA) attenuated the production of IL-8 induced by acidic DCA and CDCA
Shen et al., Int Immunopharmacol 2013 : Western blots indicated that IL-8 attenuated the oxidative stress induced high-expression of cell cycle regulation protein and inhibited the activation of p38 and NF-?B pathway