Laithwaite et al., Infect Immun 1999
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We have examined the effect of lipopolysaccharide (LPS) on LRP expression and PEA sensitivity in the macrophage-like cell line HS-P
Costales et al., Atherosclerosis 2013
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The aim of this work was to analyze whether lipopolysaccharide (LPS) can regulate LRP1 expression through SREBPs in human monocyte derived macrophages ( HMDM ) ... However, lipoproteins did not significantly alter the effect of LPS on SREBP-1 and LRP1 expression ... These results highlight a crucial role of SREBP-1 as a mediator of the downregulatory effects of LPS on LRP1 expression in human macrophages, independently of the absence or presence of modified lipoproteins