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IRF6 — MSH6
Text-mined interactions from Literome
Gupta et al., Kidney Int 2000
:
NOS2 promoter assays were conducted to identify the
effects of
alpha-MSH on
LPS + IFN-gamma mediated induction of NOS2 transcription ...
alpha-MSH ( 100 nmol/L )
inhibited the
LPS + IFN-gamma mediated induction of nuclear DNA binding activity of C/EBPbeta, but not that of NF-kappaB ( in contrast to reports in other cell types ), as well as the activity of a murine NOS2 promoter-luciferase construct
Mastronardi et al., Neuroimmunomodulation 2005
(Bacterial Infections...) :
Our results suggest that alpha-MSH increased leptin release without altering its synthesis, but when
LPS increased release and synthesis of leptin,
alpha-MSH , although further increasing release, blocked the enhanced synthesis of leptin elicited by LPS
Sobel et al., Endocr Res 1990
:
Bacterial
lipopolysaccharide (LPS) and corticotropin releasing hormone (CRH) plus arginine vasopressin (AVP)
induce immunoassayable ( 1-13 ) ACTH ( alpha
MSH ) from mononuclear leukocytes
Hwang et al., Fish Shellfish Immunol 2007
:
Japanese flounder
MSH was observed to be highly expressed in immune related tissues and are
induced by immune stimulants,
lipopolysaccharide (LPS) , polyI : C and peptidoglycan ( PG ) in vitro suggesting that it is involved in fish immunity particularly against viral and bacterial agents, a functional feature exhibited by previously reported fish cytokines