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CREB1 — PDGFB
Text-mined interactions from Literome
Stevenson et al., Exp Cell Res 2001
(Calcium Signaling) :
Block of Ran mediated nuclear import, by wheat germ agglutinin or an inactivating Ran mutant ( T24N Ran ), significantly reduced nuclear
P-CREB in
response to
PDGF-BB or membrane depolarization, but enhanced levels of P-CREB in response to forskolin ... Furthermore, blocking nuclear export with leptomycin B reduced
P-CREB stimulation by both depolarization and
PDGF-BB
Jiang et al., Chem Biol Interact 2008
:
Preincubation of RASMCs with 9 microM PNN resulted in a significant inhibition of PDGF-BB induced extracellular signal regulated kinase1/2 ( ERK1/2 ) phosphorylation expression and
PDGF-BB induced
CREB phosphorylation expression
Yao et al., J Neurosci 2012
:
Blocking TRPC1 channel suppressed PDGF mediated proliferation as well as
PDGF-BB induced
ERK/CREB and mTOR/4E-BP-p70S6K activation, thereby underscoring its role in this process